The Effectiveness and Value of Rivaroxaban and Icosapent Ethyl as Additive Therapies for Cardiovascular Disease
- PMID: 32463783
- PMCID: PMC10390898
- DOI: 10.18553/jmcp.2020.26.6.782
The Effectiveness and Value of Rivaroxaban and Icosapent Ethyl as Additive Therapies for Cardiovascular Disease
Abstract
Funding for this summary was contributed by Arnold Ventures, Commonwealth Fund, California Health Care Foundation, National Institute for Health Care Management (NIHCM), New England States Consortium Systems Organization, Blue Cross Blue Shield of Massachusetts, Harvard Pilgrim Health Care, Kaiser Foundation Health Plan, and Partners HealthCare to the Institute for Clinical and Economic Review (ICER), an independent organization that evaluates the evidence on the value of health care interventions. ICER's annual policy summit is supported by dues from Aetna, America's Health Insurance Plans, Anthem, Allergan, Alnylam, AstraZeneca, Biogen, Blue Shield of CA, Cambia Health Services, CVS, Editas, Express Scripts, Genentech/Roche, GlaxoSmithKline, Harvard Pilgrim, Health Care Service Corporation, Health Partners, Johnson & Johnson (Janssen), Kaiser Permanente, LEO Pharma, Mallinckrodt, Merck, Novartis, National Pharmaceutical Council, Premera, Prime Therapeutics, Regeneron, Sanofi, Spark Therapeutics, and United Healthcare. Pearson is employed by ICER; Synnott was employed by ICER at the time of this report. Ollendorf, Campbell, and McQueen received grants from ICER for work on this review. Ollendorf also reports advisory board, consulting, and other fees from Sarepta Therapeutics, DBV Technologies, EMD Serono, Gerson Lehman Group, The CEA Registry Sponsors, Autolus, Analysis Group, Amgen, AbbVie, Cytokinetics, Aspen Institute/University of Southern California, and University of Colorado, unrelated to this review.
Conflict of interest statement
Funding for this summary was contributed by Arnold Ventures, Commonwealth Fund, California Health Care Foundation, National Institute for Health Care Management (NIHCM), New England States Consortium Systems Organization, Blue Cross Blue Shield of Massachusetts, Harvard Pilgrim Health Care, Kaiser Foundation Health Plan, and Partners HealthCare to the Institute for Clinical and Economic Review (ICER), an independent organization that evaluates the evidence on the value of health care interventions.
ICER’s annual policy summit is supported by dues from Aetna, America’s Health Insurance Plans, Anthem, Allergan, Alnylam, AstraZeneca, Biogen, Blue Shield of CA, Cambia Health Services, CVS, Editas, Express Scripts, Genentech/Roche, GlaxoSmithKline, Harvard Pilgrim, Health Care Service Corporation, Health Partners, Johnson & Johnson (Janssen), Kaiser Permanente, LEO Pharma, Mallinckrodt, Merck, Novartis, National Pharmaceutical Council, Premera, Prime Therapeutics, Regeneron, Sanofi, Spark Therapeutics, and United Healthcare.
Pearson is employed by ICER; Synnott was employed by ICER at the time of this report. Ollendorf, Campbell, and McQueen received grants from ICER for work on this review. Ollendorf also reports advisory board, consulting, and other fees from Sarepta Therapeutics, DBV Technologies, EMD Serono, Gerson Lehman Group, The CEA Registry Sponsors, Autolus, Analysis Group, Amgen, AbbVie, Cytokinetics, Aspen Institute/University of Southern California, and University of Colorado, unrelated to this review.
Similar articles
-
Optimal treatment sequence for targeted immune modulators for the treatment of moderate to severe ulcerative colitis.J Manag Care Spec Pharm. 2021 Aug;27(8):1046-1055. doi: 10.18553/jmcp.2021.27.8.1046. J Manag Care Spec Pharm. 2021. PMID: 34337994 Free PMC article.
-
The effectiveness and value of targeted immune modulators for moderate to severe ulcerative colitis.J Manag Care Spec Pharm. 2021 Mar;27(3):405-410. doi: 10.18553/jmcp.2021.27.3.405. J Manag Care Spec Pharm. 2021. PMID: 33645245 Free PMC article.
-
Anti B-cell maturation antigen CAR T-cell and antibody drug conjugate therapy for heavily pretreated relapsed and refractory multiple myeloma.J Manag Care Spec Pharm. 2021 Sep;27(9):1315-1320. doi: 10.18553/jmcp.2021.27.9.1315. J Manag Care Spec Pharm. 2021. PMID: 34464215 Free PMC article.
-
The Effectiveness and Value of Deflazacort and Exon-Skipping Therapies for the Management of Duchenne Muscular Dystrophy.J Manag Care Spec Pharm. 2020 Apr;26(4):361-366. doi: 10.18553/jmcp.2020.26.4.361. J Manag Care Spec Pharm. 2020. PMID: 32223597 Free PMC article.
-
The Effectiveness and Value of Siponimod for Secondary Progressive Multiple Sclerosis.J Manag Care Spec Pharm. 2020 Mar;26(3):236-239. doi: 10.18553/jmcp.2020.26.3.236. J Manag Care Spec Pharm. 2020. PMID: 32105176 Free PMC article.
Cited by
-
[Cost-benefit analysis of new lipid-lowering agents].Herz. 2022 Jun;47(3):236-243. doi: 10.1007/s00059-022-05116-8. Epub 2022 Apr 25. Herz. 2022. PMID: 35467096 Review. German.
-
Global eligibility and cost effectiveness of icosapent ethyl in primary and secondary cardiovascular prevention.Front Cardiovasc Med. 2023 Aug 31;10:1220017. doi: 10.3389/fcvm.2023.1220017. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 37719970 Free PMC article. Review.
-
The potential population health impact of treating REDUCE-IT eligible US adults with Icosapent Ethyl.Am J Prev Cardiol. 2022 Apr 28;10:100345. doi: 10.1016/j.ajpc.2022.100345. eCollection 2022 Jun. Am J Prev Cardiol. 2022. PMID: 35574517 Free PMC article.
-
Omega-3 Fatty Acids and Cardiovascular Disease: A Narrative Review for Pharmacists.J Cardiovasc Pharmacol Ther. 2021 Nov;26(6):524-532. doi: 10.1177/10742484211023715. Epub 2021 Jun 30. J Cardiovasc Pharmacol Ther. 2021. PMID: 34191622 Free PMC article. Review.
References
-
- Eikelboom JW, Connolly SJ, Bosch J, et al. . Rivaroxaban with or without aspirin in stable cardiovascular disease. N Engl J Med. 2017;377(14):1319-30. - PubMed
-
- Bonaca MP, Bhatt DL, Cohen M, et al. . Long-term use of ticagrelor in patients with prior myocardial infarction. N Engl J Med. 2015;372(19):1791-800. - PubMed
-
- Bonaca MP, Storey RF, Theroux P, et al. . Efficacy and safety of ticagrelor over time in patients with prior MI in PEGASUS-TIMI 54. J Am Coll Cardiol. 2017;70(11):1368-75. - PubMed
-
- Bhatt DL, Fox KAA, Hacke W, et al. . Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. N Engl J Med. 2006;354(16):1706-17. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources