Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Aug;34(8):331-335.
doi: 10.1089/apc.2020.0103. Epub 2020 May 29.

A Case Series of Five People Living with HIV Hospitalized with COVID-19 in Chicago, Illinois

Affiliations

A Case Series of Five People Living with HIV Hospitalized with COVID-19 in Chicago, Illinois

Jessica P Ridgway et al. AIDS Patient Care STDS. 2020 Aug.

Abstract

The risk of COVID-19 among people living with HIV (PLWH) is largely unknown and there have been very few reported cases in the literature. We report a case series of five PLWH with COVID-19. We identified all patients with a diagnosis of HIV who tested positive for SARS-CoV-2 at University of Chicago Medicine between March 1, 2020, and April 7, 2020. We retrospectively collected data regarding demographics, comorbidities, medications, laboratory test results, radiology results, and outcomes associated with COVID-19. All five PLWH with COVID-19 were African American; 80% (4/5) were cisgender females. The mean age of patients was 48 years old (range 38-53). The majority of patients presented with cough, fever, and shortness of breath. Three patients had diarrhea. One patient presented with predominantly cardiac symptoms. All were taking antiretroviral therapy (ART) with CD4 count >200 cells/mm3 and suppressed HIV viral loads at the time of COVID-19 diagnosis. All five patients were hospitalized, two required supplemental oxygen, and none required mechanical ventilation. Four patients were treated with azithromycin and a cephalosporin and two were also treated with hydroxychloroquine. The median length of stay was 3 days (range 2-7). All patients recovered. More research is needed to understand the risks of COVID-19 among PLWH and the impact of ART on outcomes for patients with COVID-19.

Keywords: COVID-19; HIV; coinfection.

PubMed Disclaimer

Conflict of interest statement

No competing financial interests exist.

References

    1. Joob B, Wiwanitkit V.. SARS-CoV-2 and HIV. J Med Virol 2020. DOI: 10.1002/jmv.25782 - DOI - PMC - PubMed
    1. Mascolo S, Romanelli A, Carleo MA, Esposito V.. Could HIV infection alter the clinical course of SARS-CoV-2 infection? When less is better. J Med Virol 2020. DOI: 10.1002/jmv.25881 - DOI - PMC - PubMed
    1. Guo T, Fan Y, Chen M, et al. . Cardiovascular implications of fatal outcomes of patients with coronavirus disease 2019 (COVID-19). JAMA Cardiol 2020. DOI: 10.1001/jamacardio.2020.1017 - DOI - PMC - PubMed
    1. World Health Organization. Q&A on COVID-19, HIV and antiretrovirals. 2020. Available at: www.who.int/news-room/q-a-detail/q-a-on-covid-19-hiv-and-antiretrovirals (Last accessed May15, 2020).
    1. Thebault R, Ba Tran A, Williams V. The coronavirus is infecting and killing black Americans at an alarmingly high rate. Washington Post 2020;2020

MeSH terms