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Case Reports
. 2020 Nov-Dec:38:101752.
doi: 10.1016/j.tmaid.2020.101752. Epub 2020 May 26.

Invasive pulmonary aspergillosis complicating SARS-CoV-2 pneumonia: A diagnostic challenge

Spinello Antinori  1 , Roberto Rech  2 , Laura Galimberti  3 , Antonio Castelli  2 , Elena Angeli  3 , Tommaso Fossali  2 , Davide Bernasconi  3 , Alice Covizzi  4 , Cecilia Bonazzetti  4 , Alessandro Torre  3 , Luca Carsana  5 , Cristina Tonello  5 , Pietro Zerbi  6 , Manuela Nebuloni  6
Affiliations
Case Reports

Invasive pulmonary aspergillosis complicating SARS-CoV-2 pneumonia: A diagnostic challenge

Spinello Antinori et al. Travel Med Infect Dis. 2020 Nov-Dec.
No abstract available

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Conflict of interest statement

All the Authors: no conflict of interests to disclose.

Figures

Fig. 1
Fig. 1
(A,B,C) Sequential chest X-ray findings in a COVID-19 pneumonia complicated by invasive pulmonary aspergillosis. Interstitial opacities with focal consolidation in the right upper lobe (1A); worsening of the radiologic picture with involvement of the medium and upper right lobe and interstitial opacities in the left medium basal lobe (1B); partial regression of bilateral interstitial infiltrates (1C). 1D Autopsy lung section stained with haematoxylin and eosin showing spot of necrotizing pneumonia with several dichotomously branching septate hyphae consistent with Aspergillus spp (arrow and inset) surrounded by interstitial pneumonia with reactive atypical enlarged type II pneumocytes (arrow-heads) (H&E, 10x).1E Lung section stained with Grocott methenamine silver shows a branching septate hyphae (white arrow) 100x
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