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Comment
. 2022 May;81(5):e69.
doi: 10.1136/annrheumdis-2020-217609. Epub 2020 May 29.

Increasing incidence of autoantibody-negative RA is replicated and is partly explained by an aging population

Xanthe M E Matthijssen  1 , Tom W J Huizinga  2 , Annette H M van der Helm-van Mil  2   3
Affiliations
Comment

Increasing incidence of autoantibody-negative RA is replicated and is partly explained by an aging population

Xanthe M E Matthijssen et al. Ann Rheum Dis. 2022 May.
No abstract available

Keywords: anti-citrullinated protein antibodies; arthritis, rheumatoid; epidemiology.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1. Crude incidence of RA in the Leiden area 1994-2015 in all patients (above) and stratified for ACPA (below)
Legend: Y-axis are presented on the log-scale. Dots depict the observations per year. Fitted linear lines are depicted in bold and confidence intervals in light grey.
Figure 2
Figure 2. Crude incidence per age (A), and predicted increase in incidence due to aging of the Dutch population (B), both for ACPA-negative and ACPA-positive RA
Legend (A): Y-axis are presented on the log-scale. Dots depict the observations per age. Fitted lines are depicted in bold and confidence intervals in light grey.
See this image and copyright information in PMC

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References

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