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. 2020 Nov;48(11):1107-1110.
doi: 10.1002/dc.24467. Epub 2020 May 30.

Adamantinoma-like Ewing Sarcoma of the thyroid gland: Cytomorphologic, phenotypic and molecular features

Ijeuru Chikeka  1 , Simon Sung  1 , Patricia Tiscornia-Wasserman  1 , Adela Cimic  1
Affiliations

Adamantinoma-like Ewing Sarcoma of the thyroid gland: Cytomorphologic, phenotypic and molecular features

Ijeuru Chikeka et al. Diagn Cytopathol. 2020 Nov.

Abstract

Adamantinoma-like Ewing Sarcoma (ALES) is a rare subtype of Ewing sarcoma family of tumors (EFTs) which are defined by their EWSR1 gene rearrangements. We present a case of a 15-year old female with a swelling in her anterior neck of 4 months duration which had recently begun to rapidly grow in size. Fine needle aspiration showed a small blue round cell tumor with immunoreactivity for cytokeratin, CD99 and FLI1. Material for molecular testing was available on the resection specimen. Demonstration of t(11;22) (EWS-FLI1) was helpful in establishing the diagnosis.

Keywords: adamantinoma-like Ewing sarcoma; cytology; thyroid.

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References

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