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Comment
. 2020 Oct;73(4):993-995.
doi: 10.1016/j.jhep.2020.05.030. Epub 2020 May 28.

Single cell RNA sequencing analysis did not predict hepatocyte infection by SARS-CoV-2

Vincent De Smet  1 , Stefaan Verhulst  1 , Leo A van Grunsven  2
Affiliations
Comment

Single cell RNA sequencing analysis did not predict hepatocyte infection by SARS-CoV-2

Vincent De Smet et al. J Hepatol. 2020 Oct.
No abstract available

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Conflict of interest statement

Conflict of interest The authors declare no conflicts of interest that pertain to this work. Please refer to the accompanying ICMJE disclosure forms for further details.

Figures

Fig. 1
Fig. 1
scRNAseq analysis of ACE2 and TMPRSS2 expression in livers. (A) Schematic of liver cell types represented in the 3 publicly available scRNAseq data sets of human liver tissue. Cellular markers used for cluster identification are shown. (B) ACE2 and TMPRSS2 RNA (co)expression in liver cells. All raw cell counts were normalized, scaled and clustered using principle component analysis. Cell types were identified using the same markers as in the original papers (Fig. S1). Surface of dots represents percentage of cells with greater-than-zero RNA expression (per cell type). Color intensity represents expression value of genes.
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