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Case Reports
. 2021 Jan;82(1):159-198.
doi: 10.1016/j.jinf.2020.05.040. Epub 2020 May 27.

Follow-up study on pulmonary function and radiological changes in critically ill patients with COVID-19

Lei Zha  1 , Ya Shen  2 , Lingling Pan  3 , Mingfeng Han  2 , Gang Yang  4 , Xiaobao Teng  2 , Boris Tefsen  5
Affiliations
Case Reports

Follow-up study on pulmonary function and radiological changes in critically ill patients with COVID-19

Lei Zha et al. J Infect. 2021 Jan.
No abstract available

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Conflict of interest statement

Declaration of Competing Interest None.

Figures

Fig 1
Fig. 1
Transverse serial CT scans from a 20-year-old woman with COVID-19. (a) On admission (Day 10 from onset of symptoms): multiple areas of consolidation in bilateral lungs with peripheral and basal distribution. (b) On the day weaned from mechanical ventilation (Day 17): opacifications being dissipated into ground-glass opacities and irregular linear opacities. (c) On the day discharged from hospital (Day 21): ground-glass opacities and consolidations with decreased extent. (d) One month after discharge (Day 50): no abnormalities presented.
Fig 2
Fig. 2
Transverse serial CT scans from a 68-year-old man with COVID-19. (a) On admission (Day 7 from onset of symptoms): small air space consolidation in right lung, largely peripheral in location. (b) On the day received invasive mechanical ventilation (Day 12): Disease deteriorated with extensive ground-glass opacities, air space consolidation in bilateral lungs, mainly with peripheral and basal distribution. (c) On day 30, right pneumothorax has developed. (d) On the day discharged from hospital (Day 45): still had obvious abnormalities on bilateral lungs with gradually dissolved ground-glass opacities superimposed with irregular linear densities, partially presented as subpleural reticular opacities, cysts and bronchiectasis were also identified. (e) Two months follow-up scan (Day 60): Gradual resolution of bilateral ground-glass opacities and consolidation, with distortion of architectures and bronchiectasis. (f) Three months follow-up scan (Day 90): almost all ground-glass opacities dissolved, showing reticular densities, distortion of architectures and bronchiectasis in bilateral lungs with volume loss suggestive of fibrotic changes.
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