Vitamin D deficiency and the COVID-19 pandemic

Affiliations

¹ Gynecology Department, Centre hospitalier de Lorient, Lorient, France. Electronic address: patrick.zemb@orange.fr.
² Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.
³ Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
⁴ Department of Clinical Chemistry, University of Liège, CHU de Liège, Liège, Belgium.
⁵ Department of Rheumatology, Cochin Hospital, AP-HP, Paris, France.
⁶ Department of Physiology, Georges Pompidou European Hospital, AP-HP, Paris, France.
⁷ Medical University of South Carolina, Charleston, SC, USA.
⁸ Center of Research in Cardiovascular and Nutrition (C2VN), Aix-Marseille University & INSERM 1260, France.
⁹ Department of Clinical, Internal, Anaesthesiologic and Cardiovascular Sciences, 'Sapienza', Rome University, Viale del Policlinico 155, Rome, 00161 Italy.
¹⁰ Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
¹¹ Department of Biochemistry, Radioimmunology and Experimental Medicine, The Children's Memorial Health Institute, Warsaw, Poland.
¹² Department of Laboratory Medicine, Centre hospitalier de Lorient, Lorient, France.
¹³ Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
¹⁴ Department of Physiology, Necker-Enfants malades hospital, AP-HP, Paris, France.

PMID: 32474141
PMCID: PMC7256612
DOI: 10.1016/j.jgar.2020.05.006

Comment

Vitamin D deficiency and the COVID-19 pandemic

Patrick Zemb et al. J Glob Antimicrob Resist. 2020 Sep.

. 2020 Sep:22:133-134.

doi: 10.1016/j.jgar.2020.05.006. Epub 2020 May 29.

Authors

Affiliations

¹ Gynecology Department, Centre hospitalier de Lorient, Lorient, France. Electronic address: patrick.zemb@orange.fr.
² Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.
³ Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
⁴ Department of Clinical Chemistry, University of Liège, CHU de Liège, Liège, Belgium.
⁵ Department of Rheumatology, Cochin Hospital, AP-HP, Paris, France.
⁶ Department of Physiology, Georges Pompidou European Hospital, AP-HP, Paris, France.
⁷ Medical University of South Carolina, Charleston, SC, USA.
⁸ Center of Research in Cardiovascular and Nutrition (C2VN), Aix-Marseille University & INSERM 1260, France.
⁹ Department of Clinical, Internal, Anaesthesiologic and Cardiovascular Sciences, 'Sapienza', Rome University, Viale del Policlinico 155, Rome, 00161 Italy.
¹⁰ Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
¹¹ Department of Biochemistry, Radioimmunology and Experimental Medicine, The Children's Memorial Health Institute, Warsaw, Poland.
¹² Department of Laboratory Medicine, Centre hospitalier de Lorient, Lorient, France.
¹³ Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
¹⁴ Department of Physiology, Necker-Enfants malades hospital, AP-HP, Paris, France.

PMID: 32474141
PMCID: PMC7256612
DOI: 10.1016/j.jgar.2020.05.006

Abstract

•
Vitamin D deficiency is very common.
•
Randomised controlled trials showed that vitamin D decreases acute respiratory infections (ARIs).
•
Vitamin D deficiency is an easily modifiable factor of ARIs.
•
Daily vitamin D supplementation with moderate doses is safe and cheap.
•
Even a small decrease in COVID-19 infections would easily justify this intervention.

Keywords: Covid-19; Vitamin D; coronavirus; respiratory infections.

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Comment on

Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data.
Martineau AR, Jolliffe DA, Hooper RL, Greenberg L, Aloia JF, Bergman P, Dubnov-Raz G, Esposito S, Ganmaa D, Ginde AA, Goodall EC, Grant CC, Griffiths CJ, Janssens W, Laaksi I, Manaseki-Holland S, Mauger D, Murdoch DR, Neale R, Rees JR, Simpson S Jr, Stelmach I, Kumar GT, Urashima M, Camargo CA Jr. Martineau AR, et al. BMJ. 2017 Feb 15;356:i6583. doi: 10.1136/bmj.i6583. BMJ. 2017. PMID: 28202713 Free PMC article.

References

1. Martineau A.R., Jolliffe D.A., Hooper R.L., Greenberg L., Aloia J.F., Bergman P. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. BMJ. 2017;356:i6583. doi: 10.1136/bmj.i6583. - DOI - PMC - PubMed
1. Brighenti S., Bergman P., Martineau A.R. Vitamin D and tuberculosis: where next? J Intern Med. 2018;284:145–162. doi: 10.1111/joim.12777. - DOI - PubMed
1. Cashman K.D., Dowling K.G., Škrabáková Z., Gonzalez-Gross M., Valtueña J., De Henauw S. Vitamin D deficiency in Europe: pandemic? Am J Clin Nutr. 2016;103:1033–1044. doi: 10.3945/ajcn.115.120873. - DOI - PMC - PubMed
1. Manson J.E., Cook N.R., Lee I.M., Christen W., Bassuk S.S., Mora S. Vitamin D supplements and prevention of cancer and cardiovascular disease. N Engl J Med. 2019;380:33–44. doi: 10.1056/NEJMoa1809944. - DOI - PMC - PubMed
1. Pittas A.G., Dawson-Hughes B., Sheehan P., Ware J.H., Knowler W.C., Aroda V.R. Vitamin D supplementation and prevention of type 2 diabetes. N Engl J Med. 2019;381:520–530. doi: 10.1056/NEJMoa1900906. - DOI - PMC - PubMed

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Vitamin D deficiency and the COVID-19 pandemic

Affiliations

Vitamin D deficiency and the COVID-19 pandemic

Authors

Affiliations

Abstract

Comment on

References

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Medical