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Case Reports
. 2020 Aug 15:415:116941.
doi: 10.1016/j.jns.2020.116941. Epub 2020 May 27.

COVID-19-associated mild encephalitis/encephalopathy with a reversible splenial lesion

Misayo Hayashi  1 , Yuki Sahashi  2 , Yasutomo Baba  3 , Hiroyuki Okura  1 , Takayoshi Shimohata  4
Affiliations
Case Reports

COVID-19-associated mild encephalitis/encephalopathy with a reversible splenial lesion

Misayo Hayashi et al. J Neurol Sci. .

Abstract

  1. •

    We demonstrated the first patient with COVID-19 developing an isolated SCC lesion on brain MRI, suggestive of mild encephalitis/encephalopathy with a reversible splenial lesion (MERS).

  2. •

    MERS can be considered as a differential diagnosis for neurological symptoms of COVID-19, especially when patients develop transient cerebellar ataxia or disorientation.

Keywords: COVID-19; Clinically mild encephalitis; Encephalitis; Encephalopathy with a reversible splenial; Lesion; MERS.

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Conflict of interest statement

Declaration of Competing Interest None.

Figures

Fig. 1
Fig. 1
A: Diffusion weighted images (DWI) of brain MRI performed at the time of presentation showed high signal intensity at the site of splenium of corpus callosum. B: Apparent diffusion coefficient (ADC) map extracted from DWI demonstrated slight decrease in ADC value on the same lesion. C/D: Chest CT images revealed bilateral ground-glass opacity and segmental areas of consolidation.
See this image and copyright information in PMC

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