Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Apr;76(2):161-165.
doi: 10.1016/j.mjafi.2019.02.006. Epub 2019 May 31.

Study of platelet indices in pregnancy-induced hypertension

Jaya Manchanda  1 , Ajay Malik  2
Affiliations

Study of platelet indices in pregnancy-induced hypertension

Jaya Manchanda et al. Med J Armed Forces India. 2020 Apr.

Abstract

Background: Hypertension encountered during pregnancy could be the first sign of a preexisting pathology that can significantly attribute to unfavorable maternal, fetal, and neonatal outcomes. Resolving hypertensive disorders at an early age may not alter the course and proficiency of the disease, but timely detection and treatment can not only prevent hypertensive crisis but also alter unfavorable fetal outcomes. Ipso facto, an early cataloging plays an essential role in predicting the outcome of pregnancy, both for mother and baby. Platelet indices correlate with functional status of platelets and are an emerging risk marker for detecting an impending adverse outcome in pregnancy-induced hypertension (PIH). The aim of this study was to analyze the consociation between platelet indices and severity of PIH.

Methods: A prospective hospital-based study was undertaken on 100 cases diagnosed with PIH (preeclampsia [PE; 88 cases] and eclampsia [12 cases and 100 controls]).

Results: Most cases occurred in the age group of 22-26 years (43.3%) and in primigravidae (55.8%). Analysis of platelet volume indices (PVI) indicated mean platelet volume (MPV), platelet distribution width (PDW), and platelet-large cell ratio (P-LCR) as significant risk factors for developing hypertensive crisis. This was in concordance with the elevated blood pressures.

Conclusion: The study concludes that platelet indices are raised in patients who have PIH as compared with normal pregnancies.

Keywords: Eclampsia; Maternal mortality; Platelets; Pre-eclampsia; Pregnancy Induced Hypertension.

PubMed Disclaimer

References

    1. Vigil-De Gracia P., Montufar-Rueda C., Ruiz J. Expectant management of severe preeclampsia and preeclampsia superimposed on chronic hypertension between 24 and 34 weeks gestation. Eur J Obstet Gynecol Reprod Biol. 2003;107:24–27. - PubMed
    1. Barron W.M., Murphy M.B., Lindheimer M.D. In: Management of Hypertension during Pregnancy. 3rd ed. Raven Laragh G.H., Brenner B.M., editors. vol. 2. 1990. pp. 1809–1827. (New York: Hypertension pathophysiology, diagnosis and management).
    1. Taylor R.N. Pregnancy. Am J Obstet Gynecol. 1990;163:1691–1712. - PubMed
    1. Roccella E.J. Report of the national high blood pressure education program working group on high blood pressure in pregnancy. Am J Obstet Gynecol. 2000;183(1):S1–S2. - PubMed
    1. Lindheimer M.D. Introduction, history, controversies, and definitions. In: Lindheimer M.D., Cunningham F.G., editors; Roberts J.M., editor. 3rd ed. Elsevier; Amsterdam, The Netherlands: 2009. pp. 1–24. (Chesley's Hypertensive Disorders in Pregnancy).

LinkOut - more resources