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Case Reports
. 2020 Mar 12;8(5):905-910.
doi: 10.1002/ccr3.2785. eCollection 2020 May.

Lipase hypersecretion syndrome: A rare cutaneous manifestation of advanced pancreatic acinar cell carcinoma

Wasay Nizam  1 , Adil A Shah  1 , Fareed Rajack  2 , Asa Ramdath  1 , Tammey Naab  2 , Mallory Williams  1
Affiliations
Case Reports

Lipase hypersecretion syndrome: A rare cutaneous manifestation of advanced pancreatic acinar cell carcinoma

Wasay Nizam et al. Clin Case Rep. .

Abstract

Careful recognition of cutaneous lesions in patients with malignancies may aid in avoiding additional morbidity during end of life care.

Keywords: acinar cell carcinoma; lipase hypersecretion syndrome; neoplastic syndrome; pancreatic panniculitis.

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Conflict of interest statement

The authors declare that they have no competing interests and there are no relevant financial disclosures to report.

Figures

Figure 1
Figure 1
Characteristic extremity nodules of LHS
Figure 2
Figure 2
Characteristic extremity nodules of LHS
Figure 3
Figure 3
40× magnification of fat necrosis surrounded by neutrophils and foamy histiocytes consistent with pancreatic panniculitis
Figure 4
Figure 4
Coronal and axial cuts of an abdominal CT demonstrating pancreatic mass with duodenal invasion
Figure 5
Figure 5
Coronal and axial cuts of an abdominal CT demonstrating pancreatic mass with duodenal invasion
Figure 6
Figure 6
Endoscopic image of pancreatic mass with duodenal invasion
Figure 7
Figure 7
100× magnification of duodenal biopsy with collections of carcinoma with uniform cells and tubular formations
Figure 8
Figure 8
100× magnification of metastatic carcinoma in liver composed of high‐grade carcinoma forming sheets and tubular formations
Figure 9
Figure 9
Liver biopsy (1000× magnification) showing fine chromatin, large cherry red nucleoli (arrows) and nuclear pleomorphism
Figure 10
Figure 10
Gross picture of pancreatic panniculitis with characteristic discharge
See this image and copyright information in PMC

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