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. 2020 May 23;2020(4):omaa024.
doi: 10.1093/omcr/omaa024. eCollection 2020 Apr.

Ovarian sex cord tumour with annular tubules in a 13-year-old female: a case report

James J Yahaya  1   2 , Daudi Mshana  2 , Alex Mremi  3
Affiliations

Ovarian sex cord tumour with annular tubules in a 13-year-old female: a case report

James J Yahaya et al. Oxf Med Case Reports. .

Abstract

Sex cord tumour with annular tubules (SCTAT) is uncommon and distinctive type of sex cord-stromal tumours of the ovary which develops from sex cord cells. Most of SCTATs are strongly associated with Peutz-Jeghers syndrome (PJS) and have low malignancy potential; however, 20% of non-PJS-associated SCTATs have been reported to have high malignancy potential. Herein, we present a 13-year-old female who presented with severe abdominal pain localized in the right lower side, associated with nausea. Based on histopathological and immunohistochemical findings, the diagnosis was confirmed to be SCTAT. SCTAT of the ovary is extremely rare in the paediatric population as compared to the general population. Its occurrence among paediatrics as it was the case in the patient described in this paper may pose diagnostic challenges due to lack of clinical suspicion and therefore resulting in delay of diagnosis.

Keywords: annular tubules; ovarian tumours; sex cord tumours.

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Figures

Figure 1
Figure 1
Ring-shaped tubules: palisading epithelial cells within tubules (H&E, ×40).
Figure 2
Figure 2
Staining for calretinin: there is strong and diffuse staining of the tumour cells (IHC, ×40).
Figure 3
Figure 3
Inhibin staining: the tumour cells are strongly and diffusely stained (IHC, ×40).
Figure 4
Figure 4
Staining of CK AE1/AE3: the tumour cells are weakly stained (IHC, ×40).
See this image and copyright information in PMC

References

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