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Review
. 2020 Jun 2;172(11):ITC81-ITC96.
doi: 10.7326/AITC202006020.

Systemic Lupus Erythematosus

Marianthi Kiriakidou  1 , Cathy Lee Ching  1
Affiliations
Review

Systemic Lupus Erythematosus

Marianthi Kiriakidou et al. Ann Intern Med. .

Abstract

Systemic lupus erythematosus (lupus) is characterized by aberrant activity of the immune system, leading to variable clinical symptoms. Lupus is more prevalent in African American women and women in other ethnic minority groups. Diagnosing, treating, and identifying novel therapies for lupus is challenging because of its genetic and phenotypic heterogeneity. Lupus nephritis is the most common target-organ manifestation and requires individualized care to minimize toxicity. A multidisciplinary approach to caring for pregnant patients with lupus is essential to optimize outcomes.

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