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Case Reports
. 2020 Jun 1;7(5):e797.
doi: 10.1212/NXI.0000000000000797. Print 2020 Sep.

Acute disseminated encephalomyelitis after SARS-CoV-2 infection

Giovanni Novi  1 , Tommaso Rossi  2 , Enrico Pedemonte  2 , Laura Saitta  2 , Claudia Rolla  2 , Luca Roccatagliata  2 , Matilde Inglese  2 , Daniele Farinini  2
Affiliations
Case Reports

Acute disseminated encephalomyelitis after SARS-CoV-2 infection

Giovanni Novi et al. Neurol Neuroimmunol Neuroinflamm. .

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Figures

Figure
Figure. Brain and spine MRI
(A–C) Postgadolinium (Gd) T1-weighted (T1w) sequence of the brain in the axial plane showing 6 enhancing lesions (green arrows), most of which with ring enhancement and some of which with nodular enhancement. Incomplete ring enhancement is shown about the right temporal lesion (dashed green arrow). (D–F) T2-weighted (T2w) fat saturated sequence in the coronal plane with evidence of (D) hyperintense signal of the optic nerves bilaterally (white arrows), which is best seen when compared with the normal signal within (E) the optic chiasm and (F) the optic tracts (dashed white arrows). (G) T2w sequence of the thoracic spine in the sagittal plane showing a hyperintense spindle-like T8 lesion, involving less than 2 metameric levels (dashed yellow arrow). (H) Post-Gd T1w sequence of the spine in the axial plane at the level of T8 showing eccentric areas of enhancement respectively located posteriorly to the right and anteriorly to the left (dashed yellow arrow).
See this image and copyright information in PMC

References

    1. Pohl D, Alper G, Van Haren K, et al. Acute disseminated encephalomyelitis: updates on an inflammatory CNS syndrome. Neurology 2016;87:S38–S45. - PubMed
    1. Guan W, Ni Z, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 2020;382:1708–1720. - PMC - PubMed
    1. Helms J, Kremer S, Merdji H, et al. Neurologic features in severe SARS-CoV-2 infection. New Engl J Med Epub 2020 April 15. - PMC - PubMed
    1. Li YC, Bai WZ, Hashikawa T. The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients. J Med Virol Epub 2020 Feb 27. - PMC - PubMed

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