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Comment
. 2020 Jul 15;14(4):530-531.
doi: 10.5009/gnl20112.

Expression of Receptors for SARS-CoV-2 in the Gut of Patients with Inflammatory Bowel Disease

Giovanni Monteleone  1 , Eleonora Franzè  1 , Federica Laudisi  1
Affiliations
Comment

Expression of Receptors for SARS-CoV-2 in the Gut of Patients with Inflammatory Bowel Disease

Giovanni Monteleone et al. Gut Liver. .
No abstract available

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Conflict of interest statement

CONFLICTS OF INTEREST

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1
Heat map showing microarray based differential expression, log2 (fold change, Fc) of ACE2, ANPEP, DPP4 and TMPRSS2 genes in colonic biopsy samples isolated from inflamed tissues of patients with Crohn’s disease (CD), patients with ulcerative colitis (UC) and macroscopically and microscopically unaffected colonic mucosa of patients undergoing colon cancer screening (control). Total RNA was extracted using RNeasy Mini Kit with RNase free DNase set (Qiagen, Milan, Italy). Samples with quantified complementary DNA were sequenced in Microarray Unit of Cogentech (Milan, Italy). Hybridization was performed using the GeneChip® Hybridization, Wash and Stain Kit (Affymetrix; Thermo Fisher Scientific, Monza, Italy). Transcripts were selected on base of Fc value ≥1.5 or ≤1.5. All the transcripts present on GeneChip® array were mapped to related classes by Gene Ontology which gave the Fc generated from comparison between CD versus control and UC versus control.
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