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Review
. 2020 Jul;41(7):1667-1671.
doi: 10.1007/s10072-020-04486-3. Epub 2020 Jun 1.

The neurological manifestations of COVID-19: a review article

Hamid Reza Niazkar  1 , Behdad Zibaee  1 , Ali Nasimi  1 , Narjes Bahri  2
Affiliations
Review

The neurological manifestations of COVID-19: a review article

Hamid Reza Niazkar et al. Neurol Sci. 2020 Jul.

Abstract

Results: Various neurological manifestations have been reported in the literature associated with COVID-19, which in the current study are classified into Central Nervous System (CNS) related manifestations including headache, dizziness, impaired consciousness, acute cerebrovascular disease, epilepsy, and Peripheral Nervous System (PNS) related manifestations such as hyposmia/anosmia, hypogeusia/ageusia, muscle pain, and Guillain-Barre syndrome.

Conclusion: During the current context of COVID-19 pandemic, physicians should be aware of wide spectrum of neurological COVID-19 sign and symptoms for early diagnosis and isolation of patients. In this regard, COVID-19 has been associated with many neurological manifestations such as confusion, anosmia, and ageusia. Also, various evidences support the possible CNS roles in the COVID-19 pathophysiology. In this regard, further investigation of CNS involvement of SARS-COV-2 is suggested.

Keywords: COVID-19; Coronaviruses; Neurological symptoms; SARS-COV-2.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Deadly vicious cycle of pneumonia, hypoxia, and cardio-respiratory regulation nuclei of brain stem
See this image and copyright information in PMC

Comment in

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