Examining the State of the Science of Mammalian Embryo Model Systems: Proceedings of a Workshop
- PMID: 32484633
- Bookshelf ID: NBK557375
- DOI: 10.17226/25779
Examining the State of the Science of Mammalian Embryo Model Systems: Proceedings of a Workshop
Excerpt
Because of the recent advances in embryo modeling techniques, and at the request of the Office of Science Policy in the Office of the Director at the National Institutes of Health, the National Academies of Sciences, Engineering, hosted a 1-day public workshop that would explore the state of the science of mammalian embryo model systems. The workshop, which took place on January 17, 2020, featured a combination of presentations, panels, and general discussions, during which panelists and participants offered a broad range of perspectives. Participants considered whether embryo model systems — especially those that use nonhuman primate cells — can be used to predict the function of systems made with human cells. Presentations provided an overview of the current state of the science of in vitro development of human trophoblast. This publication summarizes the presentation and discussion of the workshop.
Copyright 2020 by the National Academy of Sciences. All rights reserved.
Sections
- The National Academies of SCIENCES • ENGINEERING • MEDICINE
- PLANNING COMMITTEE FOR A WORKSHOP ON EXAMINING THE STATE OF THE SCIENCE OF MAMMALIAN EMBRYO MODEL SYSTEMS
- Reviewers
- Acronyms and Abbreviations
- 1. Introduction and Overview
- 2. Mammalian Embryo Research and Pluripotent Stem Cells
- 3. Examining the Development of Extraembryonic Lineages
- 4. Stem Cell–Based Models of Human Embryos
- 5. Comparative Embryonic Development Across Species
- 6. Exploring Opportunities and Challenges with Mammalian Embryo Model Systems
- References
- Appendix A. Workshop Agenda
- Appendix B. Speaker Biographical Sketches
- Appendix C. Statement of Task
- Appendix D. Registered Attendees
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