Osteocalcin promotes bone mineralization but is not a hormone
- PMID: 32484816
- PMCID: PMC7266291
- DOI: 10.1371/journal.pgen.1008714
Osteocalcin promotes bone mineralization but is not a hormone
Conflict of interest statement
The author has declared that no competing interests exist.
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Comment on
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An osteocalcin-deficient mouse strain without endocrine abnormalities.PLoS Genet. 2020 May 28;16(5):e1008361. doi: 10.1371/journal.pgen.1008361. eCollection 2020 May. PLoS Genet. 2020. PMID: 32463812 Free PMC article.
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Osteocalcin is necessary for the alignment of apatite crystallites, but not glucose metabolism, testosterone synthesis, or muscle mass.PLoS Genet. 2020 May 28;16(5):e1008586. doi: 10.1371/journal.pgen.1008586. eCollection 2020 May. PLoS Genet. 2020. PMID: 32463816 Free PMC article.
References
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- Ducy P, Desbois C, Boyce B, Pinero G, Story B, et al. (1996) Increased bone formation in osteocalcin-deficient mice. Nature. 1:448–52. - PubMed
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