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Review
. 2020 Jul 10;6(7):1624-1634.
doi: 10.1021/acsinfecdis.0c00236. Epub 2020 Jun 16.

Current Perspective of Antiviral Strategies against COVID-19

Bintou A Ahidjo  1   2   3 , Marcus Wing Choy Loe  2   3 , Yan Ling Ng  2   3 , Chee Keng Mok  1   2   3 , Justin Jang Hann Chu  1   2   3   4
Affiliations
Review

Current Perspective of Antiviral Strategies against COVID-19

Bintou A Ahidjo et al. ACS Infect Dis. .

Abstract

COVID-19 was declared a pandemic by the World Health Organization on March 11, 2020. This novel coronavirus disease, caused by the SARS-CoV-2 virus, has resulted in severe and unprecedented social and economic disruptions globally. Since the discovery of COVID-19 in December 2019, numerous antivirals have been tested for efficacy against SARS-CoV-2 in vitro and also clinically to treat this disease. This review article discusses the main antiviral strategies currently employed and summarizes reported in vitro and in vivo efficacies of key antiviral compounds in use.

Keywords: COVID-19; SARS-CoV-2; antiviral; clinical trials; coronavirus; pandemic.

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