Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2020 May 28;12(5):e8328.
doi: 10.7759/cureus.8328.

Recurrence of Pheochromocytoma With Metastases After Resection of Primary Tumor

Sharini Venugopal  1 , Mamta Chhabria  1 , Michael Quartuccio  2   3
Affiliations
Case Reports

Recurrence of Pheochromocytoma With Metastases After Resection of Primary Tumor

Sharini Venugopal et al. Cureus. .

Abstract

Pheochromocytomas and paragangliomas are rare tumors that arise from the chromaffin cells of the adrenal medulla or sympathetic paravertebral ganglia, respectively. Long-term surveillance is recommended regardless of the thoroughness of surgical resection. Here, we present a patient who was diagnosed with pheochromocytoma who underwent right adrenalectomy and was lost to follow up. She presented 15 years later with recurrence and was found to have multiple metastases. Subsequent genetic testing was also negative.

Keywords: benign; malignant; mutation; pheochromocytoma; recurrence; size.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Right-sided adrenal mass lighting up on PET-dotatate scan.
PET, positron emission tomography
See this image and copyright information in PMC

References

    1. Occurrence of pheochromocytoma in Rochester, Minnesota, 1950 through 1979. Beard CM, Sheps SG, Kurland LT, et al. https://www.ncbi.nlm.nih.gov/pubmed?holding=wemllib&term=6645626. Mayo Clin Proc. 1983;58:802–804. - PubMed
    1. Thompson LD, Young WF Jr, Kawashima A, et al. World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Endocrine Organs. Lyon: IARC press; 2004. Malignant adrenal pheochromocytoma; pp. 147–150.
    1. Prognostic markers in pheochromocytoma. Clarke MR, Weyant RJ, Watson CG, et al. https://doi.org/10.1016/S0046-8177(98)90070-3. Hum Pathol. 1998;29:522–526. - PubMed
    1. Predictors of recurrence in pheochromocytoma. Press D, Akyuz M, Dural C, et al. https://doi.org/10.1016/j.surg.2014.08.044 J Am Coll Surg. 2014;156:1523–1528. - PubMed
    1. Year of diagnosis, features at presentation and risk of recurrence in patients with pheochromocytoma or secreting paraganglioma. Amar L, Servais A, Gimenez-Roqueplo AP, et al. https://doi.org/10.1210/jc.2004-1398. J Clin Endocrinol Metab. 2005;90:2110–2116. - PubMed

Publication types

LinkOut - more resources