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Book

Drug Absorption

Abdulrahman A. Alagga, Mark V. Pellegrini, Vikas Gupta  1
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Drug Absorption

Abdulrahman A. Alagga et al.
Free Books & Documents

Excerpt

Pharmacokinetics describes the study of drug absorption, distribution, metabolism, excretion, and how the body affects the drug. The application of pharmacokinetic methods to ensure patients are treated safely and effectively is known as clinical pharmacokinetics. The introduction of pharmacokinetics as a discipline has facilitated the development of rational drug therapy, the understanding of drug action and metabolism, the understanding of the concentration-effect relationship, and the establishment of dosage regimens.

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Conflict of interest statement

Disclosure: Abdulrahman Alagga declares no relevant financial relationships with ineligible companies.

Disclosure: Mark Pellegrini declares no relevant financial relationships with ineligible companies.

Disclosure: Vikas Gupta declares no relevant financial relationships with ineligible companies.

References

    1. Caldwell J, Gardner I, Swales N. An introduction to drug disposition: the basic principles of absorption, distribution, metabolism, and excretion. Toxicol Pathol. 1995 Mar-Apr;23(2):102-14. - PubMed
    1. Currie GM. Pharmacology, Part 2: Introduction to Pharmacokinetics. J Nucl Med Technol. 2018 Sep;46(3):221-230. - PubMed
    1. Mayersohn M. Drug absorption. J Clin Pharmacol. 1987 Sep;27(9):634-8. - PubMed
    1. Bielinski C, Kaoui B. Numerical method to characterise capsule membrane permeability for controlled drug delivery. Int J Numer Method Biomed Eng. 2022 Feb;38(2):e3551. - PubMed
    1. Sunakawa H, Mizoi K, Takahashi R, Takahashi S, Ogihara T. Impact of P-Glycoprotein-Mediated Drug-Endogenous Substrate Interactions on Androgen and Blood-Brain Barrier Permeability. J Pharm Sci. 2024 Jan;113(1):228-234. - PubMed

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