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Book

Aortic Insufficiency

Saikrishna Patibandla  1 , Joseph Heaton  2 , Joseph S. Azzam  3
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Aortic Insufficiency

Saikrishna Patibandla et al.
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Excerpt

Aortic regurgitation (AR), also known as aortic insufficiency, is a form of valvular heart disease in which the integrity of the aortic valve is compromised and leads to inadequate closure of the valve leaflets. A normal aortic valve is comprised of three semilunar cusps that attach to the aortic wall. Loss of function occurs when the valves themselves become diseased or if there is aortic root involvement. In AR, there is retrograde blood flow from the aorta into the left ventricle which occurs in diastole in the cardiac cycle. Chronic AR was initially described by Corrigan in 1832 in syphilitic patients who suffered from aortic root dilation. The clinical presentation of AR depends on its acuity of onset.

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Conflict of interest statement

Disclosure: Saikrishna Patibandla declares no relevant financial relationships with ineligible companies.

Disclosure: Joseph Heaton declares no relevant financial relationships with ineligible companies.

Disclosure: Joseph Azzam declares no relevant financial relationships with ineligible companies.

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