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Book

Diphenhydramine Toxicity

David A. Huynh  1 , Malak Abbas  2 , Ali Dabaja  3
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Diphenhydramine Toxicity

David A. Huynh et al.
Free Books & Documents

Excerpt

Diphenhydramine is a first-generation antihistamine with anticholinergic and sedative properties. It is most commonly used for the treatment of nausea, vomiting, allergic rhinitis, mild to severe allergic reactions (e.g., anaphylaxis), and as a mild sleep aid. While used for a wide array of medical indications, diphenhydramine is also one of the most commonly abused medications in the United States (U.S.). Acute intoxication with diphenhydramine can have severe, potentially fatal consequences if not managed appropriately in a timely manner.

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Conflict of interest statement

Disclosure: David Huynh declares no relevant financial relationships with ineligible companies.

Disclosure: Malak Abbas declares no relevant financial relationships with ineligible companies.

Disclosure: Ali Dabaja declares no relevant financial relationships with ineligible companies.

References

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