Methylene Blue
- PMID: 32491525
- Bookshelf ID: NBK557593
Methylene Blue
Excerpt
Methylene blue is a medication used in the management and treatment of methemoglobinemia, a condition in which hemoglobin decreases its ability to carry oxygen. This activity reviews the indications, action, adverse effects, and contraindications for methylene blue as a valuable agent in the therapy of methemoglobinemia, vasoplegic syndrome, Plasmodium falciparum, and ifosfamide-induced encephalopathy, as well as for diagnostic purposes such as sentinel lymph node mapping during breast procedures and parathyroid gland mapping during parathyroidectomies. This activity will highlight the indications, mechanism of action, adverse event profile, and other key factors pertinent for members of a healthcare team managing patients with methemoglobinemia and related conditions.
Copyright © 2025, StatPearls Publishing LLC.
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References
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- do Nascimento TS, Pereira RO, de Mello HL, Costa J. Methemoglobinemia: from diagnosis to treatment. Rev Bras Anestesiol. 2008 Nov-Dec;58(6):651-64. - PubMed
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- Salman AE, Salman MA, Saricaoglu F, Akinci SB, Aypar Ü. Pain on injection of propofol: a comparison of methylene blue and lidocaine. J Clin Anesth. 2011 Jun;23(4):270-4. - PubMed
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