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Book

Renal Leiomyosarcoma

Rabia Zafar  1 , Sukesh Manthri  1 , Muhammad S. Shurbaji  1
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Renal Leiomyosarcoma

Rabia Zafar et al.
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Excerpt

Renal leiomyosarcoma (LMS) is a rare and aggressive mesenchymal tumor that usually arises from the smooth muscle cells of the intrarenal blood vessels or the renal pelvis. Primary leiomyosarcomas are rare in the kidney and represent 1%-2% of all malignant renal tumors. The mean age at presentation is 50–60 years with a female preponderance.There is a high tendency of local recurrence, hence complete surgical excision is recommended. Renal LMS frequently metastasizes to distant body organs via hematogenous spread and carries an overall poor prognosis. The diagnosis of primary renal leiomyosarcoma should be made with caution. Since the prognosis for a renal sarcoma is particularly poor, differentiation from sarcomatoid renal cell carcinoma is necessary.

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Conflict of interest statement

Disclosure: Rabia Zafar declares no relevant financial relationships with ineligible companies.

Disclosure: Sukesh Manthri declares no relevant financial relationships with ineligible companies.

Disclosure: Muhammad Shurbaji declares no relevant financial relationships with ineligible companies.

References

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