Clear Cell Renal Carcinoma (Archived)
- PMID: 32491576
- Bookshelf ID: NBK557644
Clear Cell Renal Carcinoma (Archived)
Excerpt
Renal cell carcinoma (RCC) arises from the renal cortex or the renal tubular epithelial cells. It is classified into clear cell RCC (ccRCC), papillary RCC, and chromophobe RCC, accounting for about 85% of all the primary renal cancers. The other 15% constitutes of transitional cell carcinoma, Wilms tumor or nephroblastoma, tumors of the collecting ducts, and renal sarcomas. They are heterogeneous diseases with different biology, genetics, and behavior. Overall, the incidence has been steadily increasing, and currently, it is the 7th most common cancer among men. Among the genitourinary cancers, RCC has the highest mortality rate. The increase in incidence could be attributed to incidental diagnosis. About 60% of the cases are detected incidentally.
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Sections
- Introduction
- Etiology
- Epidemiology
- Pathophysiology
- Histopathology
- History and Physical
- Evaluation
- Treatment / Management
- Differential Diagnosis
- Medical Oncology
- Staging
- Prognosis
- Complications
- Consultations
- Deterrence and Patient Education
- Pearls and Other Issues
- Enhancing Healthcare Team Outcomes
- Review Questions
- References
References
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- Skinner DG, Colvin RB, Vermillion CD, Pfister RC, Leadbetter WF. Diagnosis and management of renal cell carcinoma. A clinical and pathologic study of 309 cases. Cancer. 1971 Nov;28(5):1165-77. - PubMed
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