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Book

Clear Cell Renal Carcinoma (Archived)

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Clear Cell Renal Carcinoma (Archived)

Sandeep A. Padala et al.
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Excerpt

Renal cell carcinoma (RCC) arises from the renal cortex or the renal tubular epithelial cells. It is classified into clear cell RCC (ccRCC), papillary RCC, and chromophobe RCC, accounting for about 85% of all the primary renal cancers. The other 15% constitutes of transitional cell carcinoma, Wilms tumor or nephroblastoma, tumors of the collecting ducts, and renal sarcomas. They are heterogeneous diseases with different biology, genetics, and behavior. Overall, the incidence has been steadily increasing, and currently, it is the 7th most common cancer among men. Among the genitourinary cancers, RCC has the highest mortality rate. The increase in incidence could be attributed to incidental diagnosis. About 60% of the cases are detected incidentally.

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Conflict of interest statement

Disclosure: Sandeep Padala declares no relevant financial relationships with ineligible companies.

Disclosure: Avyakta Kallam declares no relevant financial relationships with ineligible companies.

References

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