Biliary Duct Hamartoma
- PMID: 32491682
- Bookshelf ID: NBK557750
Biliary Duct Hamartoma
Excerpt
Multiple biliary duct hamartomas or “von Meyenburg complexes” are rare, benign liver malformations characterized by cystic dilated biliary ducts that were first discovered in 1918 by Von Meyenburg. They are usually incidentally found at autopsy or laparotomy due to the asymptomatic clinical course. They are usually diagnosed on imaging as single or multiple small cystic nodules ranging from 0.05 cm to 1.5 cm in size. Although incidental findings can mimic metastatic liver disease as well as other clinically significant diseases, which may prompt an extensive diagnostic work-up and even surgical intervention. Thus, proper diagnosis with specific imaging findings or confirmation with histological evaluation is required.
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Sections
- Continuing Education Activity
- Introduction
- Etiology
- Epidemiology
- Pathophysiology
- Histopathology
- History and Physical
- Evaluation
- Treatment / Management
- Differential Diagnosis
- Surgical Oncology
- Prognosis
- Complications
- Deterrence and Patient Education
- Enhancing Healthcare Team Outcomes
- Review Questions
- References
References
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- Sugawara T, Shindoh J, Hoshi D, Hashimoto M. Intrahepatic cholangiocarcinoma and portal hypertension developing in a patient with multicystic biliary microhamartomas. Malays J Pathol. 2018 Dec;40(3):331-335. - PubMed
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- Torbenson MS. Hamartomas and malformations of the liver. Semin Diagn Pathol. 2019 Jan;36(1):39-47. - PubMed
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- Lin S, Weng Z, Xu J, Wang MF, Zhu YY, Jiang JJ. A study of multiple biliary hamartomas based on 1697 liver biopsies. Eur J Gastroenterol Hepatol. 2013 Aug;25(8):948-52. - PubMed
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