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Book

Genetics, Chromosomes

Isha Pathak  1 , Bruno Bordoni  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Book

Genetics, Chromosomes

Isha Pathak et al.
Free Books & Documents

Excerpt

A chromosome is a DNA molecule that contains the genetic information for an organism. The chromosomal structure is composed of the organism's DNA and special proteins to form the dense, coiled architecture. The chromosome's tertiary structure is a crucial component in transcription regulation and cellular replication, and division.

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Conflict of interest statement

Disclosure: Isha Pathak declares no relevant financial relationships with ineligible companies.

Disclosure: Bruno Bordoni declares no relevant financial relationships with ineligible companies.

References

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    1. Tessarz P, Kouzarides T. Histone core modifications regulating nucleosome structure and dynamics. Nat Rev Mol Cell Biol. 2014 Nov;15(11):703-8. - PubMed
    1. Luger K, Dechassa ML, Tremethick DJ. New insights into nucleosome and chromatin structure: an ordered state or a disordered affair? Nat Rev Mol Cell Biol. 2012 Jun 22;13(7):436-47. - PMC - PubMed
    1. Perea-Resa C, Blower MD. Centromere Biology: Transcription Goes on Stage. Mol Cell Biol. 2018 Sep 15;38(18) - PMC - PubMed

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