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Book

Thyroid Nodule Biopsy

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Thyroid Nodule Biopsy

Dawood Tafti et al.
Free Books & Documents

Excerpt

Fine needle aspiration (FNA) was initially performed in the 1930s when Martin and Ellis first described the procedure and the potential implications in the medical field. Initially, interest in the procedure remained low due in part to concerns with regards to cancer seeding. Walfish later described the use of combined ultrasound guidance and needle aspiration cytology in increasing the diagnostic accuracy of specimen acquisition. The role of ultrasound-guided FNA has evolved over time as an important tool in the assessment of thyroid nodules.

The important aspects of the FNA procedure include:

  1. Minimizing patient discomfort

  2. Maintaining patient safety

  3. Maintaining proper ultrasound and needle technique in order to visualize needle entry to the target nodule

  4. Ensuring adequate acquisition of tissue sample

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Conflict of interest statement

Disclosure: Dawood Tafti declares no relevant financial relationships with ineligible companies.

Disclosure: Donald Schultz declares no relevant financial relationships with ineligible companies.

References

    1. Martin HE, Ellis EB. BIOPSY BY NEEDLE PUNCTURE AND ASPIRATION. Ann Surg. 1930 Aug;92(2):169-81. - PMC - PubMed
    1. Walfish PG, Hazani E, Strawbridge HT, Miskin M, Rosen IB. Combined ultrasound and needle aspiration cytology in the assessment and management of hypofunctioning thyroid nodule. Ann Intern Med. 1977 Sep;87(3):270-4. - PubMed
    1. Allen E, Fingeret A. StatPearls [Internet] StatPearls Publishing; Treasure Island (FL): 2023. Jul 24, Anatomy, Head and Neck, Thyroid. - PubMed
    1. Chaudhary V, Bano S. Thyroid ultrasound. Indian J Endocrinol Metab. 2013 Mar;17(2):219-27. - PMC - PubMed
    1. Frates MC, Benson CB, Charboneau JW, Cibas ES, Clark OH, Coleman BG, Cronan JJ, Doubilet PM, Evans DB, Goellner JR, Hay ID, Hertzberg BS, Intenzo CM, Jeffrey RB, Langer JE, Larsen PR, Mandel SJ, Middleton WD, Reading CC, Sherman SI, Tessler FN. Management of thyroid nodules detected at US: Society of Radiologists in Ultrasound consensus conference statement. Ultrasound Q. 2006 Dec;22(4):231-8; discussion 239-40. - PubMed

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