Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2020 Jun 2;31(6):1041-1043.
doi: 10.1016/j.cmet.2020.05.013.

Of Mice and Men: NAD+ Boosting with Niacin Provides Hope for Mitochondrial Myopathy Patients

Eduardo Nunes Chini  1
Affiliations
Free article
Comment

Of Mice and Men: NAD+ Boosting with Niacin Provides Hope for Mitochondrial Myopathy Patients

Eduardo Nunes Chini. Cell Metab. .
Free article

Abstract

In this issue of Cell Metabolism, Pirinen et al. (2020) show that disruption in NAD+ homeostasis is a key component of the pathogenesis of mitochondrial myopathy in humans that can be targeted by the administration of the NAD+ precursor niacin, identifying NAD+ boosting as a potential treatment for this devastating disease.

PubMed Disclaimer

Conflict of interest statement

Declaration of Interests E.N.C. receives consulting fees from TeneoBio and Calico and has a patent on small-molecule CD38 inhibitors.

Comment on

LinkOut - more resources