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. 2020 Mar;16(1):190319.
doi: 10.1183/20734735.0319-2019.

Clues beyond the lung: an unusual diagnosis in an infant with chronic lung disease

Affiliations

Clues beyond the lung: an unusual diagnosis in an infant with chronic lung disease

Rachel Walsh et al. Breathe (Sheff). 2020 Mar.

Abstract

It is important to consider alternative diagnoses when a common respiratory condition presents with atypical features. In this patient, subtle systemic signs and an unusual clinical course hinted at an unexpected aetiology. http://bit.ly/2webytn.

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Conflict of interest statement

Conflict of interest: R. Walsh has nothing to disclose. Conflict of interest: D. Batra was given a bursary to attend the Joint European Neonatal Society Conference in Venice by the British Association of Perinatal Medicine, which was funded by the Chiesi Pharmaceutical Company. This included travel and the conference fee. Conflict of interest: A. Dixit has nothing to disclose. Conflict of interest: J.M. Bhatt has nothing to disclose.

Figures

Figure 1
Figure 1
Chest radiograph on day 1.
Figure 2
Figure 2
Chest radiograph on day 14.
Figure 3
Figure 3
Axial T2 section from MRI brain scan at 4 weeks.
Figure 4
Figure 4
Chest radiograph at 3 months.
Figure 5
Figure 5
a) Coronal and (b) axial sections from CT of the chest at 11 months.

References

    1. National Institute for Health and Care Excellence Neonatal infection (early onset): antibiotics for prevention and treatment www.nice.org.uk/guidance/cg149/chapter/1-Guidance#risk-factors-for-infec.... Date last accessed: September 23, 2019. - PubMed
    1. Lu J, Sheen V. Periventricular heterotopia. Epilepsy Behav 2005; 7: 143–149. doi:10.1016/j.yebeh.2005.05.001 - DOI - PubMed
    1. Masurel-Paulet A, Haan E, Thompson E, et al. . Lung disease associated with periventricular nodular heterotopia and an FLNA mutation. Eur J Med Genet 2011; 54: 25–28. doi:10.1016/j.ejmg.2010.09.010 - DOI - PubMed
    1. Feng Y, Chen M, Moskowitz I, et al. . Filamin A (FLNA) is required for cell–cell contact in vascular development and cardiac morphogenesis. Proc Natl Acad Sci USA 2006; 103: 19836–19841. doi:10.1073/pnas.0609628104 - DOI - PMC - PubMed
    1. Sutherland-Smith A. Filamin structure, function and mechanics: are altered filamin-mediated force responses associated with human disease? Biophys Rev 2011; 3: 15–23. doi:10.1007/s12551-011-0042-y - DOI - PMC - PubMed

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