Response by Cohen et al to Letter Regarding Article, "Association of Inpatient Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Mortality Among Patients With Hypertension Hospitalized With COVID-19"

Jordana B Cohen^#^{1

2}, Thomas C Hanff^#^{2

3}, Andrew M South^{4

5}, Matthew A Sparks^{6

7}, Swapnil Hiremath⁸, Adam P Bress⁹, J Brian Byrd¹⁰, Julio A Chirinos³

Affiliations

¹ From the Renal-Electrolyte and Hypertension Division (J.B.C.), Perelman School of Medicine, University of Pennsylvania, Philadelphia.
² Department of Biostatistics, Epidemiology, and Informatics (J.B.C., T.C.H.), Perelman School of Medicine, University of Pennsylvania, Philadelphia.
³ Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania and Perelman School of Medicine, University of Pennsylvania (T.C.H., J.A.C.).
⁴ Section of Nephrology, Department of Pediatrics, Wake Forest School of Medicine and Brenner Children's Hospital, Winston-Salem, NC (A.M.S.).
⁵ Division of Public Health Sciences, Department of Epidemiology and Prevention, and Department of Surgery-Hypertension and Vascular Research, Wake Forest School of Medicine, Winston-Salem, NC (A.M.S.).
⁶ Division of Nephrology, Department of Medicine, Duke School of Medicine, Durham, NC (M.A.S.).
⁷ Renal Section, Durham Veterans Affairs Medical Center, NC (M.A.S.).
⁸ Division of Nephrology, Department of Medicine, University of Ottawa, Canada (S.H.).
⁹ Division of Health System Innovation and Research, Department of Population Health Sciences, University of Utah, Salt Lake City (A.P.B.).
¹⁰ Division of Cardiovascular Medicine, University of Michigan Medical School, Ann Arbor (J.B.B.).

^# Contributed equally.

PMID: 32496917
PMCID: PMC7265880
DOI: 10.1161/CIRCRESAHA.120.317205

Comment

Response by Cohen et al to Letter Regarding Article, "Association of Inpatient Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Mortality Among Patients With Hypertension Hospitalized With COVID-19"

Jordana B Cohen et al. Circ Res. 2020.

. 2020 Jun 5;126(12):e140-e141.

doi: 10.1161/CIRCRESAHA.120.317205. Epub 2020 Jun 4.

Authors

Jordana B Cohen^#^{1

2}, Thomas C Hanff^#^{2

3}, Andrew M South^{4

5}, Matthew A Sparks^{6

7}, Swapnil Hiremath⁸, Adam P Bress⁹, J Brian Byrd¹⁰, Julio A Chirinos³

Affiliations

¹ From the Renal-Electrolyte and Hypertension Division (J.B.C.), Perelman School of Medicine, University of Pennsylvania, Philadelphia.
² Department of Biostatistics, Epidemiology, and Informatics (J.B.C., T.C.H.), Perelman School of Medicine, University of Pennsylvania, Philadelphia.
³ Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania and Perelman School of Medicine, University of Pennsylvania (T.C.H., J.A.C.).
⁴ Section of Nephrology, Department of Pediatrics, Wake Forest School of Medicine and Brenner Children's Hospital, Winston-Salem, NC (A.M.S.).
⁵ Division of Public Health Sciences, Department of Epidemiology and Prevention, and Department of Surgery-Hypertension and Vascular Research, Wake Forest School of Medicine, Winston-Salem, NC (A.M.S.).
⁶ Division of Nephrology, Department of Medicine, Duke School of Medicine, Durham, NC (M.A.S.).
⁷ Renal Section, Durham Veterans Affairs Medical Center, NC (M.A.S.).
⁸ Division of Nephrology, Department of Medicine, University of Ottawa, Canada (S.H.).
⁹ Division of Health System Innovation and Research, Department of Population Health Sciences, University of Utah, Salt Lake City (A.P.B.).
¹⁰ Division of Cardiovascular Medicine, University of Michigan Medical School, Ann Arbor (J.B.B.).

^# Contributed equally.

PMID: 32496917
PMCID: PMC7265880
DOI: 10.1161/CIRCRESAHA.120.317205

No abstract available

PubMed Disclaimer

Comment in

Response by Zhang et al to Letter Regarding Article, "Association of Inpatient Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Mortality Among Patients With Hypertension Hospitalized With COVID-19".
Zhang P, Zhu L, Cai J, Lei F, Qin JJ, Wang Y, Yuan Y, Rohit L, Liu PP, Li H. Zhang P, et al. Circ Res. 2020 Jun 5;126(12):e142-e143. doi: 10.1161/CIRCRESAHA.120.317242. Epub 2020 Jun 4. Circ Res. 2020. PMID: 32496914 Free PMC article. No abstract available.

Comment on

Association of Inpatient Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Mortality Among Patients With Hypertension Hospitalized With COVID-19.
Zhang P, Zhu L, Cai J, Lei F, Qin JJ, Xie J, Liu YM, Zhao YC, Huang X, Lin L, Xia M, Chen MM, Cheng X, Zhang X, Guo D, Peng Y, Ji YX, Chen J, She ZG, Wang Y, Xu Q, Tan R, Wang H, Lin J, Luo P, Fu S, Cai H, Ye P, Xiao B, Mao W, Liu L, Yan Y, Liu M, Chen M, Zhang XJ, Wang X, Touyz RM, Xia J, Zhang BH, Huang X, Yuan Y, Loomba R, Liu PP, Li H. Zhang P, et al. Circ Res. 2020 Jun 5;126(12):1671-1681. doi: 10.1161/CIRCRESAHA.120.317134. Epub 2020 Apr 17. Circ Res. 2020. PMID: 32302265 Free PMC article.

References

1. Zhang P, Zhu L, Cai J, Lei F, Qin J-J, Xie J, Liu Y-M, Zhao YC, Huang X, Lin L, et al. Association of inpatient use of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers with mortality among patients with hypertension hospitalized with COVID-19. Circ Res. 2020;126:1671–1681. doi: 10.1161/CIRCRESAHA.120.317134. - PMC - PubMed
1. Murthy VL, Koupenova M, Shah RV. ACEing COVID-19: a role for angiotensin axis inhibition in SARS-CoV-2 infection? Circ Res. 2020;126:1682–1684. doi: 10.1161/CIRCRESAHA.120.317174. - PMC - PubMed
1. South AM, Diz DI, Chappell MC. COVID-19, ACE2, and the cardiovascular consequences. Am J Physiol Heart Circ Physiol. 2020;318:H1084–H1090. doi: 10.1152/ajpheart.00217.2020. - PMC - PubMed
1. Sparks MA, South A, Welling P, Luther JM, Cohen J, Byrd JB, Burrell LM, Batlle D, Tomlinson L, Bhalla V, et al. Sound science before quick judgement regarding RAS blockade in COVID-19. Clin J Am Soc Nephrol. 2020;15:714–716. doi: 10.2215/CJN.03530320. - PMC - PubMed
1. Hanff TC, Harhay MO, Brown TS, Cohen JB, Mohareb AM. Is there an association between COVID-19 mortality and the renin-angiotensin system-a call for epidemiologic investigations [published online March 26, 2020]. Clin Infect Dis. doi: 10.1093/cid/ciaa329. - PMC - PubMed

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Response by Cohen et al to Letter Regarding Article, "Association of Inpatient Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Mortality Among Patients With Hypertension Hospitalized With COVID-19"

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Response by Cohen et al to Letter Regarding Article, "Association of Inpatient Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Mortality Among Patients With Hypertension Hospitalized With COVID-19"

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