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Review
. 2020 Jul;15(3):309-319.
doi: 10.1016/j.cpet.2020.03.006.

Roles of F-18-Fluoro-2-Deoxy-Glucose PET/Computed Tomography Scans in the Management of Post-Transplant Lymphoproliferative Disease in Pediatric Patient

Yan-Feng Xu  1 , Ji-Gang Yang  2
Affiliations
Review

Roles of F-18-Fluoro-2-Deoxy-Glucose PET/Computed Tomography Scans in the Management of Post-Transplant Lymphoproliferative Disease in Pediatric Patient

Yan-Feng Xu et al. PET Clin. 2020 Jul.

Abstract

Post-transplant lymphoproliferative disease is a well-known complication in transplant recipients. Evaluating the extent and stage of disease is important for management and follow-up. As a combination of anatomic and functional imaging, PET/CT is a sensitive and specific tool to stage and detect occult disease compared with conventional imaging. PET/CT also has a role in monitoring treatment response. Although PET/CT has been shown to be potentially useful in adults, evidence in children is insufficient. This review provides an overview of the use of PET/CT in post-transplant lymphoproliferative disease, especially in pediatric patients.

Keywords: PET/CT; PTLD; Pediatrics.

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Conflict of interest statement

Disclosure Jigang YANG was partially supported by National Natural Science Foundation of China (No: 81771860, 81971642), Beijing Natural Science Foundation (No:7192041), National Key Research and Development Plan (No: 2017YFC0114003).

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