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Comment
. 2020 Sep;45(9):677-678.
doi: 10.1136/rapm-2020-101584. Epub 2020 Jun 3.

NSAIDs for analgesia in the era of COVID-19

Daniel L Herzberg  1   2 , Harry P Sukumaran  3 , Eugene Viscusi  4
Affiliations
Comment

NSAIDs for analgesia in the era of COVID-19

Daniel L Herzberg et al. Reg Anesth Pain Med. 2020 Sep.

Abstract

Globally, non-steroidal anti-inflammatory drugs (NSAIDs) are highly used to treat pain. With the rise of the COVID-19 pandemic, the safety of NSAIDs use has been called into question. These concerns are worthy of review. At present, there is no compelling data showing that NSAIDs worsen the severity of COVID-19 symptoms or increase one's likelihood of contracting the illness. For patients in pain and without symptoms that could potentially be attributed to COVID-19 (cough, fevers/chills, lethargy, myalgias, anosmia and so on), NSAIDs should continue to remain a viable option to provide analgesia to patients in need.

Keywords: acute pain; analgesia; chronic pain; pain management; pharmacology.

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Conflict of interest statement

Competing interests: None declared.

Comment on

References

    1. Rao P, Knaus EE. Evolution of nonsteroidal anti-inflammatory drugs (NSAIDs): cyclooxygenase (COX) inhibition and beyond. J Pharm Pharm Sci 2008;11:81–110. 10.18433/J3T886 - DOI - PubMed
    1. Barkin RL, Beckerman M, Blum SL, et al. . Should nonsteroidal anti-inflammatory drugs (NSAIDs) be prescribed to the older adult? Drugs Aging 2010;27:775–89. 10.2165/11539430-000000000-00000 - DOI - PubMed
    1. Fang L, Karakiulakis G, Roth M. Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? Lancet Respir Med 2020;8:e21. 10.1016/S2213-2600(20)30116-8 - DOI - PMC - PubMed
    1. Wan Y, Shang J, Graham R, et al. . Receptor recognition by the novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS coronavirus. J Virol 2020;94 10.1128/JVI.00127-20 - DOI - PMC - PubMed
    1. Krietsch Boerner L. No evidence to support link between ibuprofen and COVID-19, experts say. Chemical & Engineering News, 2020. Available: https://cen.acs.org/pharmaceuticals/evidence-support-link-between-ibupro...

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