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Comment
. 2020 Oct 1;202(7):1058-1059.
doi: 10.1164/rccm.202005-1923LE.

Reply to Dickstein: Extracorporeal CO2 Removal and the Alveolar Gas Equation

Darryl Abrams  1   2 , Antonio Pesenti  3   4 , Laurent Brochard  5   6 , Daniel Brodie  1   2
Affiliations
Comment

Reply to Dickstein: Extracorporeal CO2 Removal and the Alveolar Gas Equation

Darryl Abrams et al. Am J Respir Crit Care Med. .
No abstract available

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Figures

Figure 1.
Figure 1.
The partial pressure of alveolar oxygen (PaO2) was calculated using the simplified alveolar gas equation (dashed lines) and the complete equation (solid lines) at 3 different levels of FiO2 (0.7 [green lines], 0.5 [red lines], and 0.3 [black lines]) and across a range (from 0 to 100 ml) of CO2 elimination via ECCO2R. Baseline respiratory exchange ratio = 0.8. Note that at lower FiO2, the PaO2 curves from the simplified and complete equations become closer in approximation, with a substantial reduction in PaO2 as CO2 elimination via ECCO2R increases. ECCO2R = extracorporeal CO2 removal.
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References

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    1. Abrams D, Schmidt M, Pham T, Beitler JR, Fan E, Goligher EC, et al. Mechanical ventilation for acute respiratory distress syndrome during extracorporeal life support: research and practice. Am J Respir Crit Care Med. 2020;201:514–525. - PubMed
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