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Case Reports
. 2020 Aug;56(2):106043.
doi: 10.1016/j.ijantimicag.2020.106043. Epub 2020 Jun 2.

Tocilizumab administration in a refractory case of COVID-19

Affiliations
Case Reports

Tocilizumab administration in a refractory case of COVID-19

Farzaneh Dastan et al. Int J Antimicrob Agents. 2020 Aug.
No abstract available

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Figures

Figure 1
Fig. 1
Chest X-ray of the patient during hospitalization. (a, b and c) Progression of lower and upper lobe infiltration. (d, e and f) Recovery of infiltration after tocilizumab administration.
Figure 2
Fig. 2
Timeline of vital signs, therapeutic regimens, and laboratory results during hospitalization.

References

    1. Corman VM, Landt O, Kaiser M, Molenkamp R, Meijer A, Chu DKW, et al. Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR. Euro surveillance: bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin. 2020;25 - PMC - PubMed
    1. Zhang C, Wu Z, Li J-W, Zhao H, Wang G-Q. The cytokine release syndrome (CRS) of severe COVID-19 and Interleukin-6 receptor (IL-6R) antagonist Tocilizumab may be the key to reduce the mortality. Int J Antimicrob Agents. 2020 - PMC - PubMed
    1. Gautret P, Lagier JC, Parola P, Hoang VT, Meddeb L, Sevestre J, et al. Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: A pilot observational study. Travel Med Infect Dis. 2020;34 - PMC - PubMed
    1. Hammami MB, Garibaldi B, Shah P, Liu G, Jain T, Chen PH, et al. Clinical Course of COVID-19 in a Liver Transplant Recipient on Hemodialysis and Response to Tocilizumab Therapy: A Case Report. 2020. - PMC - PubMed
    1. Sciascia S, Apra F, Baffa A, Baldovino S, Boaro D, Boero R, et al. Pilot prospective open, single-arm multicentre study on off-label use of tocilizumab in patients with severe COVID-19. Clin Exp Rheumatol. 2020 - PubMed

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