Do snake venom cytotoxins exhibit amphiphilicity?
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- PMID: 3250282
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Do snake venom cytotoxins exhibit amphiphilicity?
An Acad Bras Cienc.
1988.
Abstract
It is suggested, on the basis of the structural information available from the literature, that the molecules of cobramine B and homologous cytotoxins, in contrast to snake venom neurotoxins, are amphiphilic in the sense that they are composed of a predominantly hydrophobic multi-stranded beta-sheet and other regions sharply hydrophilic. It is possible that the direct lytic activity of snake venom cytotoxins is due, at least in part, to their amphiphathy.
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