DNMT3A and TET2 mutations reshape hematopoiesis in opposing ways

Isaac F López-Moyado^{1

2

3}, Anjana Rao^{4

5

6}

Affiliations

¹ Division of Signaling and Gene Expression, La Jolla Institute for Immunology, La Jolla, CA, USA.
² Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.
³ Department of Pharmacology and Moores Cancer Center, University of California San Diego, La Jolla, CA, USA.
⁴ Division of Signaling and Gene Expression, La Jolla Institute for Immunology, La Jolla, CA, USA. arao@lji.org.
⁵ Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA. arao@lji.org.
⁶ Department of Pharmacology and Moores Cancer Center, University of California San Diego, La Jolla, CA, USA. arao@lji.org.

Comment

Isaac F López-Moyado et al. Nat Genet. 2020 Jun.

. 2020 Jun;52(6):554-556.

doi: 10.1038/s41588-020-0641-2.

Isaac F López-Moyado^{1

2

3}, Anjana Rao^{4

5

6}

¹ Division of Signaling and Gene Expression, La Jolla Institute for Immunology, La Jolla, CA, USA.
² Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.
³ Department of Pharmacology and Moores Cancer Center, University of California San Diego, La Jolla, CA, USA.
⁴ Division of Signaling and Gene Expression, La Jolla Institute for Immunology, La Jolla, CA, USA. arao@lji.org.
⁵ Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA. arao@lji.org.
⁶ Department of Pharmacology and Moores Cancer Center, University of California San Diego, La Jolla, CA, USA. arao@lji.org.

No abstract available

Comment on

DNA methylation disruption reshapes the hematopoietic differentiation landscape.
Izzo F, Lee SC, Poran A, Chaligne R, Gaiti F, Gross B, Murali RR, Deochand SD, Ang C, Jones PW, Nam AS, Kim KT, Kothen-Hill S, Schulman RC, Ki M, Lhoumaud P, Skok JA, Viny AD, Levine RL, Kenigsberg E, Abdel-Wahab O, Landau DA. Izzo F, et al. Nat Genet. 2020 Apr;52(4):378-387. doi: 10.1038/s41588-020-0595-4. Epub 2020 Mar 23. Nat Genet. 2020. PMID: 32203468 Free PMC article.

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