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Comment
. 2020 Aug;81(2):e145-e147.
doi: 10.1016/j.jinf.2020.05.071. Epub 2020 Jun 4.

Comparison of SARS-CoV-2 detection in nasopharyngeal swab and saliva

Sumio Iwasaki  1 , Shinichi Fujisawa  1 , Sho Nakakubo  2 , Keisuke Kamada  2 , Yu Yamashita  2 , Tatsuya Fukumoto  1 , Kaori Sato  1 , Satoshi Oguri  1 , Keisuke Taki  1 , Hajime Senjo  3 , Junichi Sugita  1 , Kasumi Hayasaka  1 , Satoshi Konno  2 , Mutsumi Nishida  1 , Takanori Teshima  4
Affiliations
Comment

Comparison of SARS-CoV-2 detection in nasopharyngeal swab and saliva

Sumio Iwasaki et al. J Infect. 2020 Aug.
No abstract available

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Detection of SAS-CoV-2 in nasopharyngeal and saliva samples. (A, B) Viral loads (A) and CT values (B) in ten COVID-19 patients according to the day after symptom onset. (C) Results of multiple PCR testing from the 10 patients according to the day after symptom onset. N, nasopharyngeal; S, saliva; +, positive; -, negative. (D, E) Viral loads (D) and CT values (E) in the patients at convalescent phase.
See this image and copyright information in PMC

Comment in

Comment on

  • Saliva is a reliable tool to detect SARS-CoV-2.
    Azzi L, Carcano G, Gianfagna F, Grossi P, Gasperina DD, Genoni A, Fasano M, Sessa F, Tettamanti L, Carinci F, Maurino V, Rossi A, Tagliabue A, Baj A. Azzi L, et al. J Infect. 2020 Jul;81(1):e45-e50. doi: 10.1016/j.jinf.2020.04.005. Epub 2020 Apr 14. J Infect. 2020. PMID: 32298676 Free PMC article.

References

    1. Azzi L., Carcano G., Gianfagna F., Grossi P., Gasperina D.D., Genoni A. Saliva is a reliable tool to detect SARS-CoV-2. J Infect. 2020 Apr 14 PubMed PMID: 32298676. - PMC - PubMed
    1. Letko M., Marzi A., Munster V. Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses. Nat Microbiol. Apr. 2020;5(4):562–569. PubMed PMID: 32094589. - PMC - PubMed
    1. To K.K., Tsang O.T., Chik-Yan Yip C., Chan K.H., Wu T.C., Chan J.M.C. Consistent detection of 2019 novel coronavirus in saliva. Clin Infect Dis. 2020 Feb 12 PubMed PMID: 32047895. Pubmed Central PMCID: PMC7108139. - PMC - PubMed
    1. To K.K., Tsang O.T., Leung W.S., Tam A.R., Wu T.C., Lung D.C. Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study. Lancet Infect Dis. May. 2020;20(5):565–574. PubMed PMID: 32213337. Pubmed Central PMCID: PMC7158907. - PMC - PubMed
    1. Wyllie A.L., Fourmier J., Casanovas-Massana A., Campbell M., Tokuyama M., Vijayakumar P. Saliva is more sensitive for SARS-CoV-2 detectionin COVID-19 patients than nasopharyngeal swabs. medRxiv. 2020