Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Nov:144:109936.
doi: 10.1016/j.mehy.2020.109936. Epub 2020 Jun 1.

Oral cancer and periodontal disease increase the risk of COVID 19? A mechanism mediated through furin and cathepsin overexpression

Thodur Madapusi Balaji  1 , Saranya Varadarajan  2 , U S Vishal Rao  3 , A Thirumal Raj  2 , Shankaragouda Patil  4 , Gururaj Arakeri  3 , Peter A Brennan  5
Affiliations

Oral cancer and periodontal disease increase the risk of COVID 19? A mechanism mediated through furin and cathepsin overexpression

Thodur Madapusi Balaji et al. Med Hypotheses. 2020 Nov.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Oral mucosa mediated SARS-corona virus-2 infection in oral cancer/periodontitis patients.
See this image and copyright information in PMC

Comment in

References

    1. Wang C., Horby P.W., Hayden F.G., Gao G.F. A novel coronavirus outbreak of global health concern. Lancet. 2020;395:470–473. doi: 10.1016/S0140-6736(20)30185-9. - DOI - PMC - PubMed
    1. Zhou P., Lou Yang X, Wang X.G., Hu B., Zhang L., Zhang W. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020;579:270–273. doi: 10.1038/s41586-020-2012-7. - DOI - PMC - PubMed
    1. Ong S.W.X., Tan Y.K., Chia P.Y., Lee T.H., Ng O.T., Wong M.S.Y. Air, surface environmental, and personal protective equipment contamination by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from a symptomatic patient. JAMA – J Am Med Assoc. 2020 doi: 10.1001/jama.2020.3227. - DOI - PMC - PubMed
    1. Xu H., Zhong L., Deng J., Peng J., Dan H., Zeng X. High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa. Int J Oral Sci. 2020;12:8. doi: 10.1038/s41368-020-0074-x. - DOI - PMC - PubMed
    1. Sharma C.G., Pradeep A.R. Plasma and crevicular fluid osteopontin levels in periodontal health and disease. J Periodontal Res. 2007;42:450–455. doi: 10.1111/j.1600-0765.2007.00968.x. - DOI - PubMed