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Case Reports
. 2020 Apr 20:14:100200.
doi: 10.1016/j.lrr.2020.100200. eCollection 2020.

Successful Treatment of Ocular Chronic Lymphocytic Leukemia with Ibrutinib: Case Report and Review of the Literature

Ayushi F Chauhan  1 , Narine Viruni  2 , T Y Alvin Liu  3 , J Fernando Arevalo  3 , Bruce D Cheson  1
Affiliations
Case Reports

Successful Treatment of Ocular Chronic Lymphocytic Leukemia with Ibrutinib: Case Report and Review of the Literature

Ayushi F Chauhan et al. Leuk Res Rep. .

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Figures

Figure 1
Figure 1
Wide field fluorescein angiography of the right eye reveals retinal vascular leakage inferonasal to the optic nerve (arrow) corresponding to the infiltrative retinal lesion on fundus photographs (A). Wide field fundus photograph of the right eye shows vitritis and multiple creamy lesions in the nasal macula and inferonasal to the optic nerve on presentation (B), and subsequent resolution of retinal lesions with residual scarring, atrophy, and hypopigmentation at 8 months follow up (C).
Figure 2
Figure 2
Optical coherence tomography (OCT) images of the right eye at initial presentation show a transition zone (arrow) from a normal retina nasally to a full thickness retinal infiltration by a hyperreflective material temporally (A); multiple retinal pigment epithelium detachments (PEDs) in the inferior macula (star) (B); and resolution of PEDs with resultant retinal atrophy at a two year follow up (C).
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