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Review
. 2020 May 19:8:341.
doi: 10.3389/fchem.2020.00341. eCollection 2020.

Recent Advances in Metal Decorated Nanomaterials and Their Various Biological Applications: A Review

Affiliations
Review

Recent Advances in Metal Decorated Nanomaterials and Their Various Biological Applications: A Review

Asim Ali Yaqoob et al. Front Chem. .

Abstract

Nanoparticles (nanoparticles) have received much attention in biological application because of their unique physicochemical properties. The metal- and metal oxide-supported nanomaterials have shown significant therapeutic effect in medical science. The mechanisms related to the interaction of nanoparticles with animal and plant cells can be used to establish its significant role and to improve their activity in health and medical applications. Various attempts have been made to discuss the antibiotic resistance and antimicrobial activity of metal-supported nanoparticles. Despite all these developments, there is still a need to investigate their performance to overcome modern challenges. In this regard, the present review examines the role of various types of metal-supported nanomaterials in different areas such as antibacterial, antifungal, anticancer, and so on. Based on the significant ongoing research and applications, it is expected that metal-supported nanomaterials play an outstanding role not only in medical but also in other important areas.

Keywords: biological application; metal oxide; nanomaterials; therapeutics; tissue engineering.

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Figures

Figure 1
Figure 1
Different types of metal-based nanomaterials.
Figure 2
Figure 2
Potential medical applications of metal Sulfide based nanoparticles (CuS nanoparticles). Adapted from Goel et al. (2014), with permission from © Wiley@VCH Verlag GmbH & Co. K GaA, Weinheim.
Figure 3
Figure 3
Formation of MOFs.
Figure 4
Figure 4
(A) Metal organic frameworks comprehensive scheme as drug delivery vehicles. (B) In vivo conditions elaborated in the deliberate discharge of drugs. Adapted with permission from Keskin and Kizilel (2011).
Figure 5
Figure 5
Summary of surface modification methods of metal-based nanoparticles.
Figure 6
Figure 6
General mechanism of antimicrobial activities of metal-based nanoparticles.
Figure 7
Figure 7
Different types of nanocarriers (nanoparticle) serve as drug delivery.
Figure 8
Figure 8
A schematic mechanism of the bone tissue engineering process by using nanoparticles and drug molecules.
Figure 9
Figure 9
Schematic presentation of metal-based nanoclusters of therapeutic applications. Adapted from Tao et al. (2015), with permission from RSC.

References

    1. Addae E., Dong X., McCoy E., Yang C., Chen W., Yang L. (2014). Investigation of antimicrobial activity of photothermal therapeutic gold/copper sulfide core/shell nanoparticles to bacterial spores and cells. J. Biol. Eng. 8:11. 10.1186/1754-1611-8-11 - DOI - PMC - PubMed
    1. Ahamed M., Alhadlaq H. A., Khan M. A., Karuppiah P., Al-Dhabi N. A. (2014). Synthesis, characterization, and antimicrobial activity of copper oxide nanoparticles. J. Nanomater. 2014, 17–21. 10.1155/2014/637858 - DOI
    1. Aishwarya S., Sanjay K. R. (2020). E. coli-based synthesis of cadmium sulfide nanoparticles, characterization, antimicrobial and cytotoxicity studies. Braz. J. Microbiol. 17, 1–10. 10.1007/s42770-020-00238-9 - DOI - PMC - PubMed
    1. Allahverdiyev A. M., Abamor E. S., Bagirova M., Rafailovich M. (2011). Antimicrobial effects of TiO2 and Ag2O nanoparticles against drug-resistant bacteria and leishmania parasites. Fut. Microbiol. 6, 933–940. 10.2217/fmb.11.78 - DOI - PubMed
    1. An J., Farha O. K., Hupp J. T., Pohl E., Yeh J. I., Rosi N. L. (2012). Metal-adeninate vertices for the construction of an exceptionally porous metal-organic framework. Nat. Commun. 3, 1–6. 10.1038/ncomms1618 - DOI - PubMed

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