Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
[Preprint]. 2020 Jun 3:2020.05.29.20116004.
doi: 10.1101/2020.05.29.20116004.

A serological assay to detect SARS-CoV-2 antibodies in at-home collected finger-prick dried blood spots

Donna Grace Karp, Kenneth Danh, David Seftel, Peter Robinson, Cheng-Ting Tsai

A serological assay to detect SARS-CoV-2 antibodies in at-home collected finger-prick dried blood spots

Donna Grace Karp et al. medRxiv. .

Update in

Abstract

Accurate surveillance of coronavirus disease 2019 (COVID-19) incidence requires large-scale testing of the population. Current testing methods require in-person collection of biospecimens by a healthcare worker, limiting access of individuals who do not have access to testing facilities while placing both the patient and healthcare worker at risk of exposure to infection. We report the development and validation of a at-home finger-prick dried blood spot collection kit and an analysis method. We demonstrated 100% sensitivity and specificity using at-home collected specimens across the US. Such methods may facilitate the conduct of unbiased serosurveys within hard to reach populations and help reduce the sample collection burden of serological testing on both health care systems and individuals alike.

PubMed Disclaimer

Publication types