Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Sep;76(3):440-441.
doi: 10.1053/j.ajkd.2020.05.009. Epub 2020 Jun 5.

IgG Antibody Response to SARS-CoV-2 Infection and Viral RNA Persistence in Patients on Maintenance Hemodialysis

An S De Vriese  1 , Marijke Reynders  2
Affiliations

IgG Antibody Response to SARS-CoV-2 Infection and Viral RNA Persistence in Patients on Maintenance Hemodialysis

An S De Vriese et al. Am J Kidney Dis. 2020 Sep.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Dynamics of (A) anti–SARS-CoV-2 IgG in serum and (B) SARS-CoV-2 viral load in upper airways. IgG measured by N-protein–based ELISA (NovaLisa, NovaTec; validated in-house; approved by the Federal Agency for Drugs and Health Products). A level > 11 NTU (“NovaTec units”) is interpreted as positive, and 9-11 NTU, as borderline. Viral load measured by a laboratory-developed semi-quantitative real-time reverse transcriptase–polymerase chain reaction (RT-PCR) targeting the N (nucleocapsid) and RdRp (RNase-dependent RNA polymerase) genes. A phocine distemper virus was used as a control to test for extraction errors or presence of inhibitors. A cycle threshold value < 40 is interpreted as positive.
See this image and copyright information in PMC

Comment in

References

    1. Melgaço J.G., Azamor T., Ano Bom A.P.D. Protective immunity after COVID-19 has been questioned: what can we do without SARS-CoV-2-IgG detection? Cell Immunol. 2020;353:104114. - PMC - PubMed
    1. Wölfel R, Corman VM, Guggemos W, et al. Virological assessment of hospitalized patients with COVID-2019. Nature. 2020;581(7809):465–469. - PubMed
    1. Okba NMA, Muller MA, Li W, et al. SARS-CoV-2 specific antibody responses in COVID-19 patients [published online ahead of print April 8, 2020]. Emerg Infect Dis. https://doi.org/10.3201/eid2607.200841. - DOI