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Editorial
. 2020 Jun 8;24(1):307.
doi: 10.1186/s13054-020-03010-5.

How I approach weaning from venoarterial ECMO

Affiliations
Editorial

How I approach weaning from venoarterial ECMO

Justin A Fried et al. Crit Care. .
No abstract available

Keywords: Cardiogenic shock ECMO; ECLS; ECMO weaning; Extracorporeal life support; VA-ECMO weaning; Venoarterial ECMO weaning.

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Conflict of interest statement

Dr. Brodie receives research support from ALung Technologies; he was previously on their medical advisory board. He has been on the medical advisory boards for Baxter, BREETHE, Xenios, and Hemovent. Dr. Fried, Dr. Masoumi, and Dr. Takeda have no disclosures.

Figures

Fig. 1
Fig. 1
VA-ECMO weaning process. *Criteria required to initiate weaning trial: (1) Phenotype is compatible with recovery (2) End-organ function is improving (3) Pa02/Fi02 > 100 (4) Vasopressors and intropes at low levels (norepinephrine ≤ 4 μg/min, dobutamine < 5 mcg/kg/min) **Any of the following criteria constitutes failure of a weaning trial: (1) MAP falls below 65–70 mmHg or decreases by more than 10 mmHg from baseline (2) Significant increase in intracardiac filling pressures (3) Deterioration in respiratory status

References

    1. Guglin M, Zucker MJ, Bazan VM, Bozkurt B, El Banayosy A, Estep JD, et al. Venoarterial ECMO for adults: JACC scientific expert panel. J Am Coll Cardiol. 2019;73(6):698–716. doi: 10.1016/j.jacc.2018.11.038. - DOI - PubMed
    1. Cheng YT, Garan AR, Sanchez J, Kurlansky P, Ando M, Cevasco M, et al. Midterm outcomes of bridge-to-recovery patients after short-term mechanical circulatory support. Ann Thorac Surg. 2019;108(2):524–530. doi: 10.1016/j.athoracsur.2019.01.060. - DOI - PubMed
    1. Garan AR, Malick WA, Habal M, Topkara VK, Fried J, Masoumi A, et al. Predictors of survival for patients with acute decompensated heart failure requiring extra-corporeal membrane oxygenation therapy. ASAIO J. 2019;65(8):781–787. doi: 10.1097/MAT.0000000000000898. - DOI - PMC - PubMed
    1. Schmidt M, Burrell A, Roberts L, Bailey M, Sheldrake J, Rycus PT, et al. Predicting survival after ECMO for refractory cardiogenic shock: the survival after veno-arterial-ECMO (SAVE)-score. Eur Heart J. 2015;36(33):2246–2256. doi: 10.1093/eurheartj/ehv194. - DOI - PubMed
    1. Garan AR, Eckhardt C, Takeda K, Topkara VK, Clerkin K, Fried J, et al. Predictors of survival and ability to wean from short-term mechanical circulatory support device following acute myocardial infarction complicated by cardiogenic shock. Eur Heart J Acute Cardiovasc Care. 2018;7(8):755–765. doi: 10.1177/2048872617740834. - DOI - PMC - PubMed

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