Nucleating a Microtubule: Put a γ-Tubulin Ring on It
- PMID: 32516593
- DOI: 10.1016/j.devcel.2020.05.018
Nucleating a Microtubule: Put a γ-Tubulin Ring on It
Abstract
The γ-tubulin ring complex (γTuRC) is a microtubule nucleator that controls when and where new microtubules form. In this issue of Developmental Cell, Consolati et al. provide much-needed insight into the mechanism of γTuRC-mediated nucleation by determining the structure of human γTuRC and performing quantitative measurements of its activity.
Copyright © 2020 Elsevier Inc. All rights reserved.
Comment on
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Microtubule Nucleation Properties of Single Human γTuRCs Explained by Their Cryo-EM Structure.Dev Cell. 2020 Jun 8;53(5):603-617.e8. doi: 10.1016/j.devcel.2020.04.019. Epub 2020 May 19. Dev Cell. 2020. PMID: 32433913 Free PMC article.
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