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. 2020 Nov;39(11):2185-2194.
doi: 10.1007/s10096-020-03925-5. Epub 2020 Jun 9.

Staphylococcus capitis isolated from bloodstream infections: a nationwide 3-month survey in 38 neonatal intensive care units

Marie Decalonne  1 , Sandra Dos Santos  2 , Rémi Gimenes  1 , Florent Goube  1 , Géraldine Abadie  3 , Saïd Aberrane  4 , Vanina Ambrogi  5 , Raoul Baron  6 , Patrick Barthelemy  7 , Isabelle Bauvin  8 , Olivier Belmonte  9 , Emilie Benabid  10 , Rafik Ben Ammar  11 , Salma Ben Hadj Yahia  12 , Yasmina Berrouane  13 , Philippe Berthelot  14 , Alain Beuchee  15 , Emmanuelle Bille  16 , Pascal Bolot  17 , Stéphanie Bordes-Couecou  18 , Antoine Bouissou  19 , Sandra Bourdon  20 , Nadège Bourgeois-Nicolaos  21 , Sophie Boyer  22 , Christian Cattoen  23 , Vincent Cattoir  24 , Chantal Chaplain  25 , Céline Chatelet  26 , Aurore Claudinon  27 , Nathalie Chautemps  28 , Hélène Cormier  29 , Céline Coroller-Bec  30 , Benjamin Cotte  31 , Carole De Chillaz  32 , Olivier Dauwalder  33 , Aude Davy  34 , Martine Delorme  35 , Maryvonne Demasure  36 , Luc Desfrere  37 , Michel Drancourt  38 , Clarisse Dupin  39 , Véronique Faraut-Derouin  40 , Arnaud Florentin  41 , Virginie Forget  42 , Nicolas Fortineau  43 , Tania Foucan  44 , Pierre Frange  16   45 , Karine Gambarotto  46 , Géraldine Gascoin  47 , Laure Gibert  20 , Jacques Gilquin  48 , Audrey Glanard  49 , Jacqueline Grando  50 , Alain Gravet  51 , Jérôme Guinard  52 , Geneviève Hery-Arnaud  53 , Claire Huart  54 , Nadia Idri  55   56 , Jean-Marc Jellimann  57 , Olivier Join-Lambert  58 , Sylvie Joron  59 , Philippe Jouvencel  60 , Marie Kempf  61 , Sophie Ketterer-Martinon  62 , Mouna Khecharem  63 , Serge Klosowski  64 , Franck Labbe  65 , Adeline Lacazette  66 , Fabrice Lapeyre  67 , Jérôme Larche  68 , Peggy Larroude  69 , Anne Le Pourhiennec  70 , Nolwenn Le Sache  71 , Sylvie Ledru  72 , Annick Lefebvre  73 , Clément Legeay  29 , Florence Lemann  74 , Claire Lesteven  75 , Marion Levast-Raffin  76 , David Leyssene  77 , Isabelle Ligi  78 , Alain Lozniewski  79 , Pierre Lureau  80 , Franck-Olivier Mallaval  42 , Edith Malpote  81 , Stéphane Marret  82 , Pascale Martres  83 , Guillaume Menard  84 , Laura Menvielle  85 , Laurent Mereghetti  86 , Véronique Merle  87 , Pascale Minery  88 , Virginie Morange  89 , Julien Mourdie  90 , Anaelle Muggeo  91 , Jean Nakhleh  92 , Marie-Noëlle Noulard  93 , Claude Olive  94 , Hugues Patural  95 , Pascale Penn  96 , Manuel Petitfrere  97 , Bruno Pozetto  98 , Brigitte Riviere  99 , Audrey Robine  100 , Christine Roques Ceschin  5 , Raymond Ruimy  101 , Amine Siali  102 , Stéphanie Soive  103 , Souad Slimani  104 , Anne-Sophie Trentesaux  105 , Dominique Trivier  26 , Christian Vandenbussche  106 , Laurent Villeneuve  107 , Evelyne Werner  108 , Stéphane Le Vu  109 , Nathalie Van Der Mee-Marquet  110   111
Affiliations

Staphylococcus capitis isolated from bloodstream infections: a nationwide 3-month survey in 38 neonatal intensive care units

Marie Decalonne et al. Eur J Clin Microbiol Infect Dis. 2020 Nov.

Abstract

To increase the knowledge about S. capitis in the neonatal setting, we conducted a nationwide 3-month survey in 38 neonatal intensive care units (NICUs) covering 56.6% of French NICU beds. We demonstrated 14.2% of S. capitis BSI (S.capBSI) among nosocomial BSIs. S.capBSI incidence rate was 0.59 per 1000 patient-days. A total of 55.0% of the S.capBSIs were late onset catheter-related BSIs. The S. capitis strains infected preterm babies (median gestational age 26 weeks, median birth weight 855 g). They were resistant to methicillin and aminoglycosides and belonged to the NRCS-A clone. Evolution was favorable in all but one case, following vancomycin treatment.

Keywords: Bloodstream catheter-related infection; NRCS-A clone; Nationwide active surveillance; Neonatal Intensive Care Unit (NICU); Neonates; Preterm babies; Staphylococcus capitis.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Location of the 38 participating centers and number of neonatal intensive care beds
Fig. 2
Fig. 2
SmaI PFGE patterns of the S. capitis strains responsible for neonatal BSI
See this image and copyright information in PMC

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