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. 2020 May 14:13:177-183.
doi: 10.2147/IJGM.S243150. eCollection 2020.

Correspondence Between the Neuropsychiatric Interview M.I.N.I. and the BDI-II and MADRS-S Self-Rating Instruments as Diagnostic Tools in Primary Care Patients with Depression

Shabnam Nejati  1 , Nashmil Ariai  1 , Cecilia Björkelund  1 , Ingmarie Skoglund  1   2 , Eva-Lisa Petersson  1   2 , Pia Augustsson  2 , Dominique Hange  1   2 , Irene Svenningsson  1   2
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Correspondence Between the Neuropsychiatric Interview M.I.N.I. and the BDI-II and MADRS-S Self-Rating Instruments as Diagnostic Tools in Primary Care Patients with Depression

Shabnam Nejati et al. Int J Gen Med. .

Abstract

Objective: To investigate the correspondence between the diagnoses received by patients with symptoms of common mental disorder attending primary care, based on the diagnostic instrument International Neuropsychiatric Interview (M.I.N.I.) and the self-assessment instruments such as Beck Depression Inventory (BDI-II) and Montgomery-Asberg Depression Rating Scale - self-rating version (MADRS-S), respectively.

Design: Data were collected from a prospective observational study, ADAS, between 2014 and 2015.

Setting: Twenty-eight primary care centers in Region Västra Gotaland, Sweden.

Patients: A total of 192 patients, 18-60 years of age, on sick leave ≥14 days, with mild/moderate depression, anxiety syndrome, and stress-related mental illness were included.

Main outcome measures: Scores of the assessment instruments (BDI-II and MADRS-S) on inclusion, sensitivity, specificity, positive (PPV) and negative predictive value (NPV) for BDI-II and MADRS-S, respectively, with M.I.N.I used as diagnostic instrument.

Results: Using M.I.N.I. as gold standard, the BDI-II and MADRS-S showed almost the same sensitivity (86.9% and 87.4%, respectively), but specificity for MADRS-S was doubled compared to BDI-II (36% and 18%, respectively). There was a significant association between MADRS-S and M.I.N.I. (p=0.027). However, the same analysis between BDI and M.I.N.I. was not statistically significant (p= 0.635). NPV and PPV were calculated from assumed prevalences (10% and 75%) and were higher for MADRS-S compared to BDI-II. The PPV differences were between 2% and 7% and NPV differences were between 3% and 19%.

Conclusion: With M.I.N.I. as gold standard, MADRS-S performs better than BDI-II as a self-assessment tool in the primary care context for depression diagnostics.

Keywords: depression; diagnostic instrument; primary care; self-assessment instrument.

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Conflict of interest statement

The authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Flow-chart over the inclusion, where 33 persons were excluded from the study and further six persons missed one or more questions of MADRS-S and/or BDI-II.
Figure 2
Figure 2
Linear diagram for PPV values calculated from different prevalences ranging between 10% and 75% for BDI-II and MADRS-S variables.
Figure 3
Figure 3
Linear diagram for NPV values calculated from different prevalences ranging between 10% and 75% for BDI-II and MADRS-S variables.
See this image and copyright information in PMC

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