Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 May 18;10(2):2045894020924325.
doi: 10.1177/2045894020924325. eCollection 2020 Apr-Jun.

Cortisol/cortisone levels and quality of life in individuals with pulmonary arterial hypertension

Affiliations

Cortisol/cortisone levels and quality of life in individuals with pulmonary arterial hypertension

Rmr Tulloh et al. Pulm Circ. .

Abstract

Individuals with pulmonary arterial hypertension experience debilitating symptoms and psychological distress which may influence their cortisol regulation. We describe associations between diurnal salivary cortisol/cortisone levels and quality of life in adults with pulmonary arterial hypertension. Findings suggest potential clinical utility of cortisol/cortisone assessment as applied to a pulmonary arterial hypertension population.

Keywords: diurnal cortisol; mental health; physical health; psychological distress; pulmonary arterial hypertension.

PubMed Disclaimer

Figures

Fig. 1.
Fig. 1.
Cortisol (a) and Cortisone (b) levels by patient participants; measured at awakening, 30 min later and in the evening in people with PAH; displays rise and fall, diurnal rhythm. Data show n = 18 participants (a) and n = 19 (b).

References

    1. Tulloh RMR, Garratt V, Tagney J, et al. A pilot randomised controlled trial investigating a mindfulness-based stress reduction (MBSR) intervention in individuals with pulmonary arterial hypertension (PAH): the PATHWAYS study. Pilot Feasibility Stud 2018; 4: 78. - PMC - PubMed
    1. Lowe B, Grafe K, Ufer C, et al. Anxiety and depression in patients with pulmonary hypertension. Psychosom Med 2004; 66: 831–836. - PubMed
    1. Harzheim D, Klose H, Pinado FP, et al. Anxiety and depression disorders in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension. Respir Res 2013; 14: 104. - PMC - PubMed
    1. McEwen BS. Protective and damaging effects of stress mediators. N Engl J Med 1998; 338: 171–179. - PubMed
    1. Adam EK, Quinn ME, Tavernier R, et al. Diurnal cortisol slopes and mental and physical health outcomes: a systematic review and meta-analysis. Psychoneuroendocrinology 2017; 83: 25–41. - PMC - PubMed

LinkOut - more resources