Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 May 26;7(6):001732.
doi: 10.12890/2020_001732. eCollection 2020.

Fatal Ischaemic Stroke During COVID-19 and Acute Lung Injury

Iris Duroi  1 , Frederik Van Durme  1 , Tony Bruyns  2 , Sofie Louage  2 , Alex Heyse  1
Affiliations

Fatal Ischaemic Stroke During COVID-19 and Acute Lung Injury

Iris Duroi et al. Eur J Case Rep Intern Med. .

Abstract

Severe COVID-19 may predispose to both venous and arterial thrombosis. We describe a patient with acute ischaemic stroke while suffering from COVID-19 and respiratory failure, necessitating mechanical ventilation. Deep sedation may delay diagnosis.

Learning points: A thrombotic stroke can complicate severe COVID-19.Prolonged deep sedation during mechanical ventilation of COVID-19 patients may delay the diagnosis of stroke.The hypercoagulability and a thrombo-inflammatory response in COVID-19 is characterized by an increase in D-dimers and fibrinogen.

Keywords: ARDS; COVID-19; acute respiratory distress syndrome; stroke; thrombosis.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interests: The Authors declare that there are no competing interests.

Figures

Figure 1
Figure 1
Chest x-ray on admission showing bilateral opacities
Figure 2
Figure 2
CT scan of the brain showing a large infarct with hypodensity in the territory of the middle cerebral artery in addition to oedema and midline shift
Figure 3
Figure 3
CT scan showing a hyperdense artery sign in the sellar region (large arrow) at the transition of the left internal carotid artery to the origin of the middle cerebral artery compared with patent vessels on the right (small arrow)
See this image and copyright information in PMC

References

    1. Helms J, Kremer S, Merdji H, Clere-Jehl R, Schenck M, Kummerlen C, et al. Neurologic features of severe Sars-CoV2 infection. N Engl J Med. 2020 Apr 15; doi: 10.1056/NEJMc2008597. [Epub ahead of print] - DOI - PMC - PubMed
    1. Tavazzi G, Civardi L, Caneva L, Mongodi S, Mojoli F. Thrombotic events in SARS-CoV2 patients: an urgent call for ultrasound screening. Intensive Care Med. 2020 Apr 22; doi: 10.1007/s00134-020-06040-3. [Epub ahead of print] - DOI - PMC - PubMed
    1. Klok FA, Kruip MJHA, van der Meer NJM, Arbous MS, Gommers D, Kant KM, et al. Incidence of thrombotic complication in critically ill ICU patients with COVID-19. Thromb Res. 2020 Apr 10; doi: 10.1016/j.thromres.2020.04.013. pii: S0049-3848(20)30120-1. [Epub ahead of print] - DOI - PMC - PubMed
    1. Mao L, Jin H, Wang M, Hu Y, Chen S, He Q, et al. Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China. JAMA Neurol. 2020 Apr 10; doi: 10.1001/jamaneurol.2020.1127. [Epub ahead of print] - DOI - PMC - PubMed
    1. Oxley T, Mocco J, Majidi S, Kellner CP, Shoirah H, Singh IP, et al. Large-vessel stroke as presenting feature of Covid-19 in the young. N Engl J Med. 2020 Apr 28; doi: 10.1056/NEJMc2009787. [Epub ahead of print] - DOI - PMC - PubMed

LinkOut - more resources